| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE50854.1 | AEE52126.1 | Halhy_2990 | Halhy_4282 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: chu:CHU_3721 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504773668; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | 0.973 |
| AEE50854.1 | AEE53971.1 | Halhy_2990 | Halhy_6149 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048; KEGG: phe:Phep_2925 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504775551; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | 0.971 |
| AEE50854.1 | asd | Halhy_2990 | Halhy_1283 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.993 |
| AEE50854.1 | dapA | Halhy_2990 | Halhy_3772 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.945 |
| AEE50854.1 | dapB | Halhy_2990 | Halhy_1092 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.517 |
| AEE50854.1 | hisI | Halhy_2990 | Halhy_3812 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Histidine biosynthesis bifunctional protein hisIE; InterPro IPR008179:IPR002496; KEGG: mtt:Ftrac_3210 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; IMG reference gene:2504773196; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.846 |
| AEE50854.1 | lysA | Halhy_2990 | Halhy_0086 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.539 |
| AEE50854.1 | murE | Halhy_2990 | Halhy_1157 | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-d iaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.408 |
| AEE52126.1 | AEE50854.1 | Halhy_4282 | Halhy_2990 | COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: chu:CHU_3721 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504773668; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | 0.973 |
| AEE52126.1 | AEE53971.1 | Halhy_4282 | Halhy_6149 | COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: chu:CHU_3721 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504773668; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048; KEGG: phe:Phep_2925 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504775551; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | 0.923 |
| AEE52126.1 | asd | Halhy_4282 | Halhy_1283 | COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: chu:CHU_3721 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504773668; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.972 |
| AEE52126.1 | dapA | Halhy_4282 | Halhy_3772 | COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: chu:CHU_3721 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504773668; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.490 |
| AEE52126.1 | dapB | Halhy_4282 | Halhy_1092 | COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: chu:CHU_3721 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504773668; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.605 |
| AEE52126.1 | hisI | Halhy_4282 | Halhy_3812 | COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: chu:CHU_3721 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504773668; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Histidine biosynthesis bifunctional protein hisIE; InterPro IPR008179:IPR002496; KEGG: mtt:Ftrac_3210 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; IMG reference gene:2504773196; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.640 |
| AEE52126.1 | lysA | Halhy_4282 | Halhy_0086 | COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: chu:CHU_3721 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504773668; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.898 |
| AEE53971.1 | AEE50854.1 | Halhy_6149 | Halhy_2990 | COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048; KEGG: phe:Phep_2925 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504775551; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | COGs: COG0527 Aspartokinase; InterProIPR001048:IPR002912:IPR005106:IPR001342:IPR 001341; KEGG: chu:CHU_0073 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Bifunctional protein: aspartokinase I; homoserine dehydrogenase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504772364; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT dom [...] | 0.971 |
| AEE53971.1 | AEE52126.1 | Halhy_6149 | Halhy_4282 | COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048; KEGG: phe:Phep_2925 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504775551; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR001341; KEGG: chu:CHU_3721 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504773668; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | 0.923 |
| AEE53971.1 | asd | Halhy_6149 | Halhy_1283 | COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048; KEGG: phe:Phep_2925 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504775551; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.981 |
| AEE53971.1 | dapA | Halhy_6149 | Halhy_3772 | COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048; KEGG: phe:Phep_2925 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504775551; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.575 |
| AEE53971.1 | dapB | Halhy_6149 | Halhy_1092 | COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048; KEGG: phe:Phep_2925 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartate kinase; TIGRFAM: Aspartate kinase region; IMG reference gene:2504775551; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.519 |
