| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48004.1 | AEE48152.1 | Halhy_0091 | Halhy_0239 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | 0.945 |
| AEE48004.1 | AEE49495.1 | Halhy_0091 | Halhy_1604 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | 0.903 |
| AEE48004.1 | AEE50369.1 | Halhy_0091 | Halhy_2496 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.912 |
| AEE48004.1 | AEE50577.1 | Halhy_0091 | Halhy_2709 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR004393:IPR002638; KEGG: lby:Lbys_2650 nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Nicotinate-nucleotide diphosphorylase; TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; IMG reference gene:2504772080; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/Mo [...] | 0.964 |
| AEE48004.1 | AEE51353.1 | Halhy_0091 | Halhy_3498 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 5 nucleotidase deoxy cytosolic type C; COGs: COG4502 conserved hypothetical protein; InterPro IPR010708; KEGG: sli:Slin_1355 5 nucleotidase deoxy cytosolic type C; SPTR: 5 nucleotidase deoxy cytosolic type C; IMG reference gene:2504772879; PFAM: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). | 0.901 |
| AEE48004.1 | AEE53528.1 | Halhy_0091 | Halhy_5705 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinamidase; COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: ote:Oter_4507 nicotinamidase; PFAM: Isochorismatase-like; PRIAM: Nicotinamidase; SPTR: Nicotinamidase; IMG reference gene:2504775103; PFAM: Isochorismatase family. | 0.994 |
| AEE48004.1 | AEE53849.1 | Halhy_0091 | Halhy_6026 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | HAD-superfamily hydrolase, subfamily IIA; COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR006357:IPR005834; KEGG: phe:Phep_0089 HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: N-acetylglucosamine-6-phoshatase or p-nitrophenyl phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; IMG reference gene:2504775428; TIGRFAM: HAD-superfamily subfamily IIA hydrolase, TIGR01457; Haloacid Dehalogenase Superfamily Class (subfamily) IIA. | 0.900 |
| AEE48004.1 | AEE53950.1 | Halhy_0091 | Halhy_6128 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: sli:Slin_4342 metallophosphoesterase; PFAM: Metallophosphoesterase; PRIAM: 5'-nucleotidase; SPTR: Metallophosphoesterase; IMG reference gene:2504775530; PFAM: Calcineurin-like phosphoesterase. | 0.903 |
| AEE48004.1 | nadD | Halhy_0091 | Halhy_3374 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.943 |
| AEE48004.1 | surE | Halhy_0091 | Halhy_5066 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.904 |
| AEE48152.1 | AEE48004.1 | Halhy_0239 | Halhy_0091 | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.945 |
| AEE48152.1 | AEE49495.1 | Halhy_0239 | Halhy_1604 | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | 0.927 |
| AEE48152.1 | AEE50369.1 | Halhy_0239 | Halhy_2496 | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.902 |
| AEE48152.1 | AEE50577.1 | Halhy_0239 | Halhy_2709 | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR004393:IPR002638; KEGG: lby:Lbys_2650 nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Nicotinate-nucleotide diphosphorylase; TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; IMG reference gene:2504772080; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/Mo [...] | 0.928 |
| AEE48152.1 | AEE51353.1 | Halhy_0239 | Halhy_3498 | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | 5 nucleotidase deoxy cytosolic type C; COGs: COG4502 conserved hypothetical protein; InterPro IPR010708; KEGG: sli:Slin_1355 5 nucleotidase deoxy cytosolic type C; SPTR: 5 nucleotidase deoxy cytosolic type C; IMG reference gene:2504772879; PFAM: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). | 0.900 |
| AEE48152.1 | AEE53849.1 | Halhy_0239 | Halhy_6026 | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | HAD-superfamily hydrolase, subfamily IIA; COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR006357:IPR005834; KEGG: phe:Phep_0089 HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: N-acetylglucosamine-6-phoshatase or p-nitrophenyl phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; IMG reference gene:2504775428; TIGRFAM: HAD-superfamily subfamily IIA hydrolase, TIGR01457; Haloacid Dehalogenase Superfamily Class (subfamily) IIA. | 0.900 |
| AEE48152.1 | AEE53950.1 | Halhy_0239 | Halhy_6128 | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: sli:Slin_4342 metallophosphoesterase; PFAM: Metallophosphoesterase; PRIAM: 5'-nucleotidase; SPTR: Metallophosphoesterase; IMG reference gene:2504775530; PFAM: Calcineurin-like phosphoesterase. | 0.906 |
| AEE48152.1 | nadD | Halhy_0239 | Halhy_3374 | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.928 |
| AEE48152.1 | surE | Halhy_0239 | Halhy_5066 | Cytidyltransferase-related domain protein; COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: gym:GYMC10_6274 cytidyltransferase-related domain protein; SPTR: Cytidyltransferase-related domain protein; IMG reference gene:2504769591; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; cytidyltransferase-related domain. | Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| AEE49495.1 | AEE48004.1 | Halhy_1604 | Halhy_0091 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.903 |