| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE47968.1 | AEE48019.1 | Halhy_0054 | Halhy_0106 | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | 0.479 |
| AEE48018.1 | AEE48019.1 | Halhy_0105 | Halhy_0106 | KEGG: dfe:Dfer_2270 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769455. | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | 0.548 |
| AEE48019.1 | AEE47968.1 | Halhy_0106 | Halhy_0054 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.479 |
| AEE48019.1 | AEE48018.1 | Halhy_0106 | Halhy_0105 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | KEGG: dfe:Dfer_2270 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769455. | 0.548 |
| AEE48019.1 | AEE48020.1 | Halhy_0106 | Halhy_0107 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | rRNA (guanine-N(2)-)-methyltransferase; COGs: COG1092 SAM-dependent methyltransferase; InterPro IPR002478:IPR003402; KEGG: sli:Slin_0528 methyltransferase; PFAM: Protein of unknown function Met10; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: Methyltransferase; IMG reference gene:2504769457; PFAM: S-adenosylmethionine-dependent methyltransferase. | 0.507 |
| AEE48019.1 | AEE48753.1 | Halhy_0106 | Halhy_0848 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | InterPro IPR007409; KEGG: fps:FP1054 hypothetical protein; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504770208. | 0.638 |
| AEE48019.1 | AEE48979.1 | Halhy_0106 | Halhy_1081 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR000184; KEGG: fba:FIC_02065 surface antigen (D15); PFAM: Bacterial surface antigen (D15); SPTR: Surface antigen (D15); IMG reference gene:2504770442; PFAM: Surface antigen. | 0.448 |
| AEE48019.1 | AEE49693.1 | Halhy_0106 | Halhy_1807 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | Peroxidase; COGs: COG0450 Peroxiredoxin; InterPro IPR000866:IPR019479; KEGG: cpi:Cpin_1201 peroxidase; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin, C-terminal; PRIAM: Peroxidase; SPTR: Peroxidase; IMG reference gene:2504771168; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family. | 0.475 |
| AEE48019.1 | AEE50499.1 | Halhy_0106 | Halhy_2630 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | KEGG: ran:Riean_1147 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772001. | 0.446 |
| AEE48019.1 | AEE50594.1 | Halhy_0106 | Halhy_2726 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | KEGG: cpi:Cpin_6967 DNA-directed RNA polymerase, omega subunit; SPTR: DNA-directed RNA polymerase, omega subunit; IMG reference gene:2504772097; PFAM: RNA polymerase Rpb6. | 0.654 |
| AEE48019.1 | AEE51809.1 | Halhy_0106 | Halhy_3961 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | KEGG: cpi:Cpin_0535 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504773346. | 0.516 |
| AEE48019.1 | AEE53591.1 | Halhy_0106 | Halhy_5768 | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | WbqC-like family protein; InterPro IPR014985; KEGG: bfs:BF0144 hypothetical protein; PFAM: WbqC-like protein family; SPTR: Putative uncharacterized protein; IMG reference gene:2504775166; PFAM: WbqC-like protein family. | 0.442 |
| AEE48020.1 | AEE48019.1 | Halhy_0107 | Halhy_0106 | rRNA (guanine-N(2)-)-methyltransferase; COGs: COG1092 SAM-dependent methyltransferase; InterPro IPR002478:IPR003402; KEGG: sli:Slin_0528 methyltransferase; PFAM: Protein of unknown function Met10; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: Methyltransferase; IMG reference gene:2504769457; PFAM: S-adenosylmethionine-dependent methyltransferase. | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | 0.507 |
| AEE48753.1 | AEE48019.1 | Halhy_0848 | Halhy_0106 | InterPro IPR007409; KEGG: fps:FP1054 hypothetical protein; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504770208. | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | 0.638 |
| AEE48753.1 | AEE48979.1 | Halhy_0848 | Halhy_1081 | InterPro IPR007409; KEGG: fps:FP1054 hypothetical protein; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504770208. | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR000184; KEGG: fba:FIC_02065 surface antigen (D15); PFAM: Bacterial surface antigen (D15); SPTR: Surface antigen (D15); IMG reference gene:2504770442; PFAM: Surface antigen. | 0.536 |
| AEE48753.1 | AEE50499.1 | Halhy_0848 | Halhy_2630 | InterPro IPR007409; KEGG: fps:FP1054 hypothetical protein; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504770208. | KEGG: ran:Riean_1147 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772001. | 0.697 |
| AEE48753.1 | AEE50594.1 | Halhy_0848 | Halhy_2726 | InterPro IPR007409; KEGG: fps:FP1054 hypothetical protein; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504770208. | KEGG: cpi:Cpin_6967 DNA-directed RNA polymerase, omega subunit; SPTR: DNA-directed RNA polymerase, omega subunit; IMG reference gene:2504772097; PFAM: RNA polymerase Rpb6. | 0.770 |
| AEE48753.1 | AEE51809.1 | Halhy_0848 | Halhy_3961 | InterPro IPR007409; KEGG: fps:FP1054 hypothetical protein; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504770208. | KEGG: cpi:Cpin_0535 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504773346. | 0.641 |
| AEE48753.1 | AEE53591.1 | Halhy_0848 | Halhy_5768 | InterPro IPR007409; KEGG: fps:FP1054 hypothetical protein; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504770208. | WbqC-like family protein; InterPro IPR014985; KEGG: bfs:BF0144 hypothetical protein; PFAM: WbqC-like protein family; SPTR: Putative uncharacterized protein; IMG reference gene:2504775166; PFAM: WbqC-like protein family. | 0.532 |
| AEE48979.1 | AEE48019.1 | Halhy_1081 | Halhy_0106 | Surface antigen (D15); COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR000184; KEGG: fba:FIC_02065 surface antigen (D15); PFAM: Bacterial surface antigen (D15); SPTR: Surface antigen (D15); IMG reference gene:2504770442; PFAM: Surface antigen. | Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: cpi:Cpin_2013 phosphodiesterase, MJ0936 family; PFAM: Metallophosphoesterase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; IMG reference gene:2504769456; TIGRFAM: phosphoesterase, MJ0936 family. | 0.448 |