| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48047.1 | AEE48048.1 | Halhy_0134 | Halhy_0135 | Hypothetical protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. | COGs: COG1138 Cytochrome c biogenesis factor; InterPro IPR002541; KEGG: cpi:Cpin_3078 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c assembly protein; IMG reference gene:2504769487; PFAM: Cytochrome C assembly protein. | 0.976 |
| AEE48047.1 | AEE48049.1 | Halhy_0134 | Halhy_0136 | Hypothetical protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | 0.553 |
| AEE48048.1 | AEE48047.1 | Halhy_0135 | Halhy_0134 | COGs: COG1138 Cytochrome c biogenesis factor; InterPro IPR002541; KEGG: cpi:Cpin_3078 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c assembly protein; IMG reference gene:2504769487; PFAM: Cytochrome C assembly protein. | Hypothetical protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. | 0.976 |
| AEE48048.1 | AEE48049.1 | Halhy_0135 | Halhy_0136 | COGs: COG1138 Cytochrome c biogenesis factor; InterPro IPR002541; KEGG: cpi:Cpin_3078 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c assembly protein; IMG reference gene:2504769487; PFAM: Cytochrome C assembly protein. | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | 0.553 |
| AEE48049.1 | AEE48047.1 | Halhy_0136 | Halhy_0134 | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | Hypothetical protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. | 0.553 |
| AEE48049.1 | AEE48048.1 | Halhy_0136 | Halhy_0135 | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | COGs: COG1138 Cytochrome c biogenesis factor; InterPro IPR002541; KEGG: cpi:Cpin_3078 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c assembly protein; IMG reference gene:2504769487; PFAM: Cytochrome C assembly protein. | 0.553 |
| AEE48049.1 | AEE52199.1 | Halhy_0136 | Halhy_4355 | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | ATPase BadF/BadG/BcrA/BcrD type; COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: bfs:BF0368 hypothetical protein; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; SPTR: Putative uncharacterized protein; IMG reference gene:2504773741; PFAM: BadF/BadG/BcrA/BcrD ATPase family. | 0.413 |
| AEE48049.1 | panB | Halhy_0136 | Halhy_6178 | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.540 |
| AEE48049.1 | panC | Halhy_0136 | Halhy_2634 | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.557 |
| AEE48049.1 | panD | Halhy_0136 | Halhy_3377 | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.402 |
| AEE52199.1 | AEE48049.1 | Halhy_4355 | Halhy_0136 | ATPase BadF/BadG/BcrA/BcrD type; COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: bfs:BF0368 hypothetical protein; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; SPTR: Putative uncharacterized protein; IMG reference gene:2504773741; PFAM: BadF/BadG/BcrA/BcrD ATPase family. | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | 0.413 |
| panB | AEE48049.1 | Halhy_6178 | Halhy_0136 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | 0.540 |
| panB | panC | Halhy_6178 | Halhy_2634 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.996 |
| panB | panD | Halhy_6178 | Halhy_3377 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.970 |
| panC | AEE48049.1 | Halhy_2634 | Halhy_0136 | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | 0.557 |
| panC | panB | Halhy_2634 | Halhy_6178 | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.996 |
| panC | panD | Halhy_2634 | Halhy_3377 | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.998 |
| panD | AEE48049.1 | Halhy_3377 | Halhy_0136 | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | Domain of unknown function DUF2520-containing protein; InterPro IPR004455:IPR018931; KEGG: acd:AOLE_13460 NADP oxidoreductase coenzyme F420-dependent family protein; PFAM: Domain of unknown function DUF2520; NADP oxidoreductase, coenzyme F420-dependent; SPTR: Putative uncharacterized protein; IMG reference gene:2504769488; PFAM: NADP oxidoreductase coenzyme F420-dependent; Domain of unknown function (DUF2520). | 0.402 |
| panD | panB | Halhy_3377 | Halhy_6178 | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.970 |
| panD | panC | Halhy_3377 | Halhy_2634 | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.998 |
