Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE48057.1COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: htu:Htur_4659 N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase; SPTR: N-acylglucosamine 2-epimerase superfamily; IMG reference gene:2504769496; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase). (454 aa)    
Predicted Functional Partners:
AEE47952.1
Hypothetical protein; COGs: COG2152 glycosylase; KEGG: rmr:Rmar_2440 glycosidase PH1107-related protein; SPTR: Glycosidase PH1107-related protein; IMG reference gene:2504769388.
 
   
 0.750
AEE53364.1
Glycosidase related protein; Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose; Belongs to the glycosyl hydrolase 130 family.
 
   
 0.745
AEE53600.1
COGs: COG4124 Beta-mannanase; InterPro IPR000805; KEGG: rmr:Rmar_0467 mannan endo-1,4-beta-mannosidase; PFAM: Glycoside hydrolase, family 26; PRIAM: Mannan endo-1,4-beta-mannosidase; SPTR: Putative uncharacterized protein; IMG reference gene:2504775175; PFAM: Glycosyl hydrolase family 26; Belongs to the glycosyl hydrolase 26 family.
 
   
 0.710
AEE48056.1
Glyoxalase/bleomycin resistance protein/dioxygenase; COGs: COG2764 conserved hypothetical protein; InterPro IPR004360; KEGG: lpa:lpa_03561 putative protein conserved in bacteria; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase; IMG reference gene:2504769495; PFAM: 3-demethylubiquinone-9 3-methyltransferase.
       0.628
miaB
(Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
       0.466
AEE48055.1
Transcriptional regulator, AraC family; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR018060:IPR002818:IPR000005; KEGG: chu:CHU_3787 transcriptional regulator; PFAM: Helix-turn-helix, AraC type; ThiJ/PfpI; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family protein; manually curated; IMG reference gene:2504769494; PFAM: DJ-1/PfpI family; Bacterial regulatory helix-turn-helix proteins, AraC family.
  
    0.460
AEE48059.1
Sigma54 specific transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078:IPR002197; KEGG: cpi:Cpin_5917 sigma54 specific transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Sigma54 specific transcriptional regulator, Fis family; IMG reference gene:2504769498; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
       0.445
AEE48060.1
KEGG: coc:Coch_0313 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769499.
       0.445
AEE52473.1
COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: zpr:ZPR_0356 Na+/glucose symporter; PFAM: Sodium/solute symporter; SPTR: Na+/glucose symporter; IMG reference gene:2504774029; PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.443
AEE53599.1
COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: zpr:ZPR_0356 Na+/glucose symporter; PFAM: Sodium/solute symporter; SPTR: Na+/glucose symporter; IMG reference gene:2504775174; PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.441
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.