Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEE48060.1KEGG: coc:Coch_0313 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769499. (173 aa)    
Predicted Functional Partners:
AEE48059.1
Sigma54 specific transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078:IPR002197; KEGG: cpi:Cpin_5917 sigma54 specific transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Sigma54 specific transcriptional regulator, Fis family; IMG reference gene:2504769498; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
       0.811
miaB
(Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
  
    0.791
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.787
AEE50101.1
InterPro IPR005632; KEGG: cpi:Cpin_1054 outer membrane chaperone Skp (OmpH); PFAM: Outer membrane chaperone Skp (OmpH); SPTR: Outer membrane chaperone Skp (OmpH); IMG reference gene:2504771586; PFAM: Outer membrane protein (OmpH-like).
  
     0.746
AEE51043.1
InterPro IPR005632; KEGG: cpi:Cpin_1054 outer membrane chaperone Skp (OmpH); PFAM: Outer membrane chaperone Skp (OmpH); SPTR: Outer membrane protein; IMG reference gene:2504772562; PFAM: Outer membrane protein (OmpH-like).
  
     0.743
AEE48061.1
COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: aca:ACP_2163 ATPase, AAA family; PFAM: ATPase associated with various cellular activities, AAA-4; SPTR: ATPase, AAA family; IMG reference gene:2504769500; PFAM: Divergent AAA domain.
       0.709
AEE48062.1
Phage-related regulatory protein CII; COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cja:CJA_1579 phage-related regulatory protein CII; SPTR: Phage-related regulatory protein cII; IMG reference gene:2504769501; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
       0.709
AEE49883.1
KEGG: fba:FIC_00688 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771364; PFAM: Protein of unknown function (DUF3109).
  
     0.703
AEE51437.1
COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754; KEGG: zpr:ZPR_0488 uroporphyrinogen-III synthase; PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrinogen-III synthase; IMG reference gene:2504772964; PFAM: Uroporphyrinogen-III synthase HemD.
  
     0.696
AEE52016.1
KEGG: phe:Phep_0010 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504773556.
  
     0.688
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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