STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEE48098.1Pyruvate carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482; KEGG: zpr:ZPR_1998 biotin carboxylase; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: Pyruvate carboxylase; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; IMG reference gene:2504769537; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRF [...] (512 aa)    
Predicted Functional Partners:
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.957
AEE50389.1
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.931
AEE50107.1
Urea amidolyase related protein; COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: bcl:ABC3772 hypothetical protein; PFAM: Allophanate hydrolase subunit 2; PRIAM: Urea carboxylase; SMART: Allophanate hydrolase subunit 2; SPTR: Putative uncharacterized protein; TIGRFAM: Allophanate hydrolase subunit 2; IMG reference gene:2504771593; PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain.
 
  
 0.912
AEE48111.1
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain.
 0.910
AEE49094.1
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: fjo:Fjoh_2546 propionyl-CoA carboxylase; PFAM: Carboxyl transferase; PRIAM: Methylcrotonoyl-CoA carboxylase; SPTR: Propionyl-CoA carboxylase; IMG reference gene:2504770558; PFAM: Carboxyl transferase domain.
 
 0.891
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 
 0.876
AEE51434.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004408:IPR004143; KEGG: sli:Slin_3003 biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; SPTR: Biotin-acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; IMG reference gene:2504772961; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
 
  
 0.825
AEE52829.1
COGs: COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase beta subunit; InterPro IPR004165:IPR012792:IPR012791; KEGG: sli:Slin_1533 3-oxoacid CoA-transferase, B subunit; PFAM: Coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, subunit B; 3-oxoacid CoA-transferase, subunit A; IMG reference gene:2504774396; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; 3-oxoacid CoA-transferase, A subunit.
  
 
 0.766
AEE50433.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.742
AEE48984.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410; KEGG: ppn:Palpr_0687 (AcyL-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SPTR: (Acyl-carrier-protein) S-malonyltransferase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; IMG reference gene:2504770447; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
  
 0.734
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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