| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48098.1 | AEE48111.1 | Halhy_0185 | Halhy_0198 | Pyruvate carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482; KEGG: zpr:ZPR_1998 biotin carboxylase; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: Pyruvate carboxylase; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; IMG reference gene:2504769537; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRF [...] | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | 0.879 |
| AEE48098.1 | AEE52165.1 | Halhy_0185 | Halhy_4321 | Pyruvate carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482; KEGG: zpr:ZPR_1998 biotin carboxylase; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: Pyruvate carboxylase; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; IMG reference gene:2504769537; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRF [...] | Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089; KEGG: mtt:Ftrac_3017 biotin/lipoyl attachment domain-containing protein; PFAM: Biotin/lipoyl attachment; SPTR: Biotin carboxyl carrier protein; IMG reference gene:2504773707; PFAM: Biotin-requiring enzyme. | 0.518 |
| AEE48111.1 | AEE48098.1 | Halhy_0198 | Halhy_0185 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | Pyruvate carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482; KEGG: zpr:ZPR_1998 biotin carboxylase; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: Pyruvate carboxylase; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; IMG reference gene:2504769537; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRF [...] | 0.879 |
| AEE48111.1 | AEE49481.1 | Halhy_0198 | Halhy_1590 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: mrb:Mrub_2924 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770951; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.803 |
| AEE48111.1 | AEE49484.1 | Halhy_0198 | Halhy_1593 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: gfo:GFO_2173 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770954; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.803 |
| AEE48111.1 | AEE50388.1 | Halhy_0198 | Halhy_2515 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.870 |
| AEE48111.1 | AEE52010.1 | Halhy_0198 | Halhy_4164 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | methylmalonyl-CoA epimerase; InterPro IPR004360:IPR017515; KEGG: sli:Slin_5823 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Methylmalonyl-CoA epimerase; TIGRFAM: Methylmalonyl-CoA epimerase; IMG reference gene:2504773550; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase. | 0.973 |
| AEE48111.1 | AEE52165.1 | Halhy_0198 | Halhy_4321 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089; KEGG: mtt:Ftrac_3017 biotin/lipoyl attachment domain-containing protein; PFAM: Biotin/lipoyl attachment; SPTR: Biotin carboxyl carrier protein; IMG reference gene:2504773707; PFAM: Biotin-requiring enzyme. | 0.954 |
| AEE48111.1 | AEE52309.1 | Halhy_0198 | Halhy_4468 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: sli:Slin_1742 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; SPTR: Aldehyde Dehydrogenase; IMG reference gene:2504773855; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | 0.830 |
| AEE48111.1 | AEE53008.1 | Halhy_0198 | Halhy_5182 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR010061; KEGG: cpi:Cpin_3442 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: Methylmalonate-semialdehyde dehydrogenase (acylating); SPTR: Methylmalonate-semialdehyde dehydrogenase (Acylating); TIGRFAM: Methylmalonate-semialdehyde dehydrogenase; IMG reference gene:2504774580; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | 0.915 |
| AEE48111.1 | AEE53202.1 | Halhy_0198 | Halhy_5377 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: cpi:Cpin_7110 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; IMG reference gene:2504774775; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. | 0.935 |
| AEE48111.1 | AEE53858.1 | Halhy_0198 | Halhy_6035 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.916 |
| AEE49481.1 | AEE48111.1 | Halhy_1590 | Halhy_0198 | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: mrb:Mrub_2924 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770951; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | 0.803 |
| AEE49481.1 | AEE49484.1 | Halhy_1590 | Halhy_1593 | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: mrb:Mrub_2924 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770951; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: gfo:GFO_2173 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770954; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.933 |
| AEE49481.1 | AEE52309.1 | Halhy_1590 | Halhy_4468 | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: mrb:Mrub_2924 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770951; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: sli:Slin_1742 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; SPTR: Aldehyde Dehydrogenase; IMG reference gene:2504773855; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | 0.921 |
| AEE49481.1 | AEE53008.1 | Halhy_1590 | Halhy_5182 | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: mrb:Mrub_2924 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770951; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR010061; KEGG: cpi:Cpin_3442 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: Methylmalonate-semialdehyde dehydrogenase (acylating); SPTR: Methylmalonate-semialdehyde dehydrogenase (Acylating); TIGRFAM: Methylmalonate-semialdehyde dehydrogenase; IMG reference gene:2504774580; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. | 0.932 |
| AEE49481.1 | AEE53858.1 | Halhy_1590 | Halhy_6035 | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: mrb:Mrub_2924 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770951; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.821 |
| AEE49484.1 | AEE48111.1 | Halhy_1593 | Halhy_0198 | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: gfo:GFO_2173 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770954; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: lby:Lbys_1917 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; IMG reference gene:2504769550; PFAM: Carboxyl transferase domain. | 0.803 |
| AEE49484.1 | AEE49481.1 | Halhy_1593 | Halhy_1590 | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: gfo:GFO_2173 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770954; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: mrb:Mrub_2924 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770951; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.933 |
| AEE49484.1 | AEE52309.1 | Halhy_1593 | Halhy_4468 | (S)-3-amino-2-methylpropionate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: gfo:GFO_2173 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; IMG reference gene:2504770954; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: sli:Slin_1742 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; SPTR: Aldehyde Dehydrogenase; IMG reference gene:2504773855; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. | 0.921 |