Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEE48112.1COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. (402 aa)    
Predicted Functional Partners:
AEE48531.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: pdi:BDI_1377 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase; IMG reference gene:2504769978; PFAM: Prephenate dehydratase; ACT domain.
 
 
 0.988
AEE49080.1
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: chu:CHU_3776 glutamate synthase (NADH) large subunit; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (NADH) large subunit; IMG reference gene:2504770544; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
 
 0.945
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.926
AEE52037.1
COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518; KEGG: fjo:Fjoh_3435 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; IMG reference gene:2504773577; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase.
 
 0.926
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.918
AEE53974.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: phe:Phep_1507 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504775554; PFAM: Aminotransferase class I and II.
  
  
 
0.918
AEE52161.1
COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sli:Slin_5637 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionine beta-lyase; IMG reference gene:2504773703; PFAM: Cys/Met metabolism PLP-dependent enzyme.
  
 
 0.914
AEE48533.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: cpi:Cpin_1939 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; IMG reference gene:2504769980; PFAM: Prephenate dehydrogenase.
  
 
 0.913
AEE52476.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR005931:IPR015590; KEGG: lby:Lbys_3137 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase; PRIAM: 1-pyrroline-5-carboxylate dehydrogenase; SPTR: Delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: Delta-1-pyrroline-5-carboxylate dehydrogenase 1; IMG reference gene:2504774032; PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1.
   
 0.913
AEE54120.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: rmr:Rmar_2129 Glu/Leu/Phe/Val dehydrogenase; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region; Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; PRIAM: Glutamate dehydrogenase (NAD(P)(+)); SPTR: Glu/Leu/Phe/Val dehydrogenase; IMG reference gene:2504775708; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.911
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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