Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEE48132.1Hemolytic enterotoxin; InterPro IPR008414; KEGG: ppr:PBPRB1474 hypothetical protein; PFAM: Bacillus haemolytic enterotoxin; SPTR: Putative uncharacterized protein; IMG reference gene:2504769571; PFAM: Bacillus haemolytic enterotoxin (HBL). (388 aa)    
Predicted Functional Partners:
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.685
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.660
groL-2
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.660
AEE48131.1
Hypothetical protein; IMG reference gene:2504769570.
       0.658
AEE48133.1
Hemolytic enterotoxin; InterPro IPR008414; KEGG: aha:AHA_2582 hypothetical protein; PFAM: Bacillus haemolytic enterotoxin; SPTR: Putative uncharacterized protein; IMG reference gene:2504769572; PFAM: Bacillus haemolytic enterotoxin (HBL).
      
0.631
AEE50442.1
InterPro IPR003594; KEGG: mpi:Mpet_2164 ATP-binding region ATPase domain-containing protein; PFAM: ATP-binding region, ATPase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504771942; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 
 0.572
AEE51460.1
ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity.
   
 
 0.572
AEE51969.1
Phenylacetic acid degradation protein paaN; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR002539:IPR011966; KEGG: rmr:Rmar_1556 phenylacetic acid degradation protein PaaN; PFAM: MaoC-like dehydratase; Aldehyde dehydrogenase; PRIAM: Aldehyde dehydrogenase (NAD(+)); SPTR: NAD-dependent aldehyde dehydrogenases; TIGRFAM: Phenylacetic acid degradation protein paaN; IMG reference gene:2504773509; PFAM: MaoC like domain; Aldehyde dehydrogenase family; TIGRFAM: phenylacetic acid degradation protein paaN.
  
 
 0.561
AEE49255.1
3-hydroxybutyryl-CoA epimerase; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753:IPR006176:IPR006108; KEGG: rmr:Rmar_1469 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxybutyryl-CoA epimerase; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; IMG reference gene:2504770721; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
   
 
  0.555
AEE53201.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108:IPR001753; KEGG: phe:Phep_3724 3-hydroxyacyl-CoA dehydrogenase NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Crotonase, core; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; IMG reference gene:2504774774; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
   
 
  0.555
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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