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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
Score
AEE48171.1Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (190 aa)    
Predicted Functional Partners:
cmk
COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR000623:IPR011994; KEGG: cat:CA2559_10343 putative cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504769514; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
    
  0.910
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.910
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
   
  0.907
AEE48896.1
COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain.
    
  0.903
AEE51353.1
5 nucleotidase deoxy cytosolic type C; COGs: COG4502 conserved hypothetical protein; InterPro IPR010708; KEGG: sli:Slin_1355 5 nucleotidase deoxy cytosolic type C; SPTR: 5 nucleotidase deoxy cytosolic type C; IMG reference gene:2504772879; PFAM: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C).
    
  0.903
AEE53250.1
Phosphoribosyltransferase; COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: cpi:Cpin_5885 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; IMG reference gene:2504774823; PFAM: Phosphoribosyl transferase domain.
    
  0.903
AEE53771.1
COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: mtt:Ftrac_2535 phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase/uridine kinase; PRIAM: Uridine kinase; SPTR: Uridine kinase; IMG reference gene:2504775348; PFAM: Phosphoribulokinase / Uridine kinase family.
    
 0.903
AEE49495.1
5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
     
  0.900
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
  0.900
tdk
COGs: COG1435 Thymidine kinase; HAMAP: Thymidine kinase, subgroup; InterPro IPR020634:IPR001267; KEGG: cpi:Cpin_1517 thymidine kinase; PFAM: Thymidine kinase; PRIAM: Thymidine kinase; SPTR: Thymidine kinase; IMG reference gene:2504773565; PFAM: Thymidine kinase.
     
  0.900
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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