Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (347 aa)    
Predicted Functional Partners:
AEE48199.1
tRNA 2-selenouridine synthase; COGs: COG2603 ATPase; InterPro IPR001763:IPR017582; KEGG: sli:Slin_4991 tRNA 2-selenouridine synthase; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: tRNA 2-selenouridine synthase; TIGRFAM: tRNA 2-selenouridine synthase; IMG reference gene:2504769642; PFAM: Rhodanese-like domain; TIGRFAM: tRNA 2-selenouridine synthase.
 
   
 0.965
AEE50452.1
Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789:IPR013027; KEGG: sli:Slin_6098 response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Signal transduction response regulator, receiver region; PRIAM: Thioredoxin-disulfide reductase; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504771953; PFAM: [...]
    
 0.908
AEE54182.1
Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
    
 0.908
AEE53705.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR005982:IPR013027; KEGG: phe:Phep_1613 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin-disulfide reductase; TIGRFAM: Thioredoxin reductase; IMG reference gene:2504775280; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
     
 0.906
AEE53711.1
COGs: COG0492 Thioredoxin reductase; HAMAP: Ferredoxin--NADP reductase; InterPro IPR013027; KEGG: rbi:RB2501_08440 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Ferredoxin--NADP(+) reductase; SPTR: Thioredoxin reductase; IMG reference gene:2504775286; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
     
 0.906
AEE48200.1
COGs: COG0408 Coproporphyrinogen III oxidase; InterPro IPR001260; KEGG: dfe:Dfer_2369 coproporphyrinogen III oxidase; PFAM: Coproporphyrinogen III oxidase; PRIAM: Coproporphyrinogen oxidase; SPTR: Coproporphyrinogen oxidase; IMG reference gene:2504769643; PFAM: Coproporphyrinogen III oxidase.
       0.773
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 
 0.737
AEE53631.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: cpi:Cpin_1845 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; IMG reference gene:2504775206; PFAM: Aminotransferase class-V.
  
 
 0.572
AEE52700.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR006311:IPR001450; KEGG: mtt:Ftrac_3687 quinol:cytochrome c oxidoreductase iron-sulfur protein precursor; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Quinol:cytochrome c oxidoreductase iron-sulfur protein; IMG reference gene:2504774265.
     
 0.474
AEE48201.1
Purine or other phosphorylase family 1; COGs: COG2820 Uridine phosphorylase; InterPro IPR000845; KEGG: cpi:Cpin_4693 purine or other phosphorylase family 1; PFAM: Nucleoside phosphorylase; SPTR: Purine nucleoside phosphorylase II; IMG reference gene:2504769644; PFAM: Phosphorylase superfamily.
       0.452
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.