Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
queEHypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (228 aa)    
Predicted Functional Partners:
AEE52684.1
Queuosine biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: vex:VEA_003152 queuosine biosynthesis QueD PTPS-I; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: 6-pyruvoyl-tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; IMG reference gene:2504774247; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
 
 
 0.994
araB
Ribulokinase; COGs: COG1069 Ribulose kinase; HAMAP: L-ribulokinase; InterPro IPR005929:IPR018484:IPR018485; KEGG: ssm:Spirs_3429 L-ribulokinase; PFAM: Carbohydrate kinase, FGGY, C-terminal; Carbohydrate kinase, FGGY, N-terminal; PRIAM: Ribulokinase; SPTR: Ribulokinase; TIGRFAM: L-ribulokinase; IMG reference gene:2504769708; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: L-ribulokinase.
       0.522
folE
COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: cts:Ctha_0487 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1 2; TIGRFAM: GTP cyclohydrolase I; IMG reference gene:2504770198; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
  
  
 0.495
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.477
mutS2
MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.470
rlmH
Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
   
    0.429
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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