| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48416.1 | AEE50821.1 | Halhy_0506 | Halhy_2957 | COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: cpi:Cpin_0936 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-strand binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504769862; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.905 |
| AEE48416.1 | AEE51486.1 | Halhy_0506 | Halhy_3634 | COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: cpi:Cpin_0936 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-strand binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504769862; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.788 |
| AEE48416.1 | mutL | Halhy_0506 | Halhy_3342 | COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: cpi:Cpin_0936 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-strand binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504769862; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). | DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.419 |
| AEE48416.1 | priA | Halhy_0506 | Halhy_0381 | COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: cpi:Cpin_0936 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-strand binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504769862; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.837 |
| AEE50593.1 | priA | Halhy_2725 | Halhy_0381 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.636 |
| AEE50821.1 | AEE48416.1 | Halhy_2957 | Halhy_0506 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: cpi:Cpin_0936 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-strand binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504769862; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). | 0.905 |
| AEE50821.1 | AEE51486.1 | Halhy_2957 | Halhy_3634 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.786 |
| AEE50821.1 | priA | Halhy_2957 | Halhy_0381 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.835 |
| AEE51486.1 | AEE48416.1 | Halhy_3634 | Halhy_0506 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: cpi:Cpin_0936 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-strand binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504769862; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). | 0.788 |
| AEE51486.1 | AEE50821.1 | Halhy_3634 | Halhy_2957 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.786 |
| AEE51486.1 | pheT | Halhy_3634 | Halhy_2838 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterProIPR004532:IPR002547:IPR005146:IPR005147:IPR 005121; KEGG: phe:Phep_0825 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/B4 tRNA-binding domain; tRNA-binding region; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SPTR: Phenylalanine--tRNA ligase; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; IMG reference gene:2504772211; PFAM: tRNA synthetase B5 domain; B3/4 domain; [...] | 0.416 |
| AEE51486.1 | priA | Halhy_3634 | Halhy_0381 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.602 |
| AEE51486.1 | pth | Halhy_3634 | Halhy_2963 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.578 |
| fmt | mutS | Halhy_1571 | Halhy_1093 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.404 |
| fmt | pheT | Halhy_1571 | Halhy_2838 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterProIPR004532:IPR002547:IPR005146:IPR005147:IPR 005121; KEGG: phe:Phep_0825 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/B4 tRNA-binding domain; tRNA-binding region; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SPTR: Phenylalanine--tRNA ligase; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; IMG reference gene:2504772211; PFAM: tRNA synthetase B5 domain; B3/4 domain; [...] | 0.540 |
| fmt | priA | Halhy_1571 | Halhy_0381 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.778 |
| fmt | pth | Halhy_1571 | Halhy_2963 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.436 |
| mfd | mutL | Halhy_3470 | Halhy_3342 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.566 |
| mfd | priA | Halhy_3470 | Halhy_0381 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.640 |
| mfd | pth | Halhy_3470 | Halhy_2963 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.719 |
