Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEE48399.1L-iditol 2-dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: phe:Phep_2739 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; PRIAM: L-iditol 2-dehydrogenase; SPTR: Alcohol dehydrogenase GroES domain protein; IMG reference gene:2504769845; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (348 aa)    
Predicted Functional Partners:
AEE48400.1
Alpha-L-fucosidase; KEGG: cpi:Cpin_7192 alpha-L-fucosidase; PRIAM: Alpha-L-fucosidase; SPTR: Alpha-L-fucosidase; IMG reference gene:2504769846.
 
    0.601
AEE51986.1
InterPro IPR008000; KEGG: cpi:Cpin_1991 protein of unknown function DUF718; PFAM: Rhamnose mutarotase; SPTR: Putative uncharacterized protein; IMG reference gene:2504773526; PFAM: Domain of unknown function (DUF718).
 
     0.528
AEE48398.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: phe:Phep_1151 periplasmic binding protein/LacI transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Putative uncharacterized protein; IMG reference gene:2504769844; PFAM: Bacterial regulatory proteins, lacI family; family.
   
 
 0.504
AEE52242.1
Tagaturonate reductase; COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118; KEGG: sli:Slin_1247 mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal; PRIAM: Tagaturonate reductase; SPTR: Mannitol dehydrogenase domain protein; IMG reference gene:2504773785; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
 
   
 0.497
AEE51983.1
Amidohydrolase 2; COGs: COG3618 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: cpi:Cpin_1992 amidohydrolase 2; PFAM: Amidohydrolase 2; SPTR: Amidohydrolase 2; IMG reference gene:2504773523; PFAM: Amidohydrolase.
 
  
 0.492
AEE54329.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...]
     
 0.479
AEE53489.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.453
AEE48086.1
Alanine--glyoxylate transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR002575:IPR016047:IPR005814; KEGG: fbc:FB2170_15008 hypothetical protein; PFAM: Aminotransferase class-III; Aminoglycoside phosphotransferase; Peptidase M23; PRIAM: Alanine--glyoxylate transaminase; SPTR: Putative uncharacterized protein; IMG reference gene:2504769525; PFAM: Aminotransferase class-III; Peptidase family M23; Phosphotransferase enzyme family.
 
 
 0.452
AEE52243.1
COGs: COG2721 Altronate dehydratase; InterPro IPR007392; KEGG: sli:Slin_4785 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase, C-terminal; PRIAM: Altronate dehydratase; SPTR: Altronate dehydratase; IMG reference gene:2504773786; PFAM: SAF domain; D-galactarate dehydratase / Altronate hydrolase, C terminus.
 
   
 0.446
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.407
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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