Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEE48415.1Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107:IPR002104; KEGG: ran:Riean_0325 integrase family protein; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Integrase family protein; IMG reference gene:2504769861; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; Belongs to the 'phage' integrase family. (355 aa)    
Predicted Functional Partners:
AEE48416.1
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: cpi:Cpin_0936 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-strand binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504769862; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
 
   
 0.744
AEE48413.1
Helix-turn-helix domain protein; InterPro IPR001387; KEGG: sun:SUN_1612 transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator; IMG reference gene:2504769859; PFAM: Helix-turn-helix.
  
  
 0.503
AEE48414.1
HipA domain protein; COGs: COG3550 conserved hypothetical protein; InterPro IPR012894:IPR012893; KEGG: aca:ACP_1546 HipA family protein; PFAM: HipA-like, C-terminal; HipA-like, N-terminal; SPTR: HipA family protein; IMG reference gene:2504769860; PFAM: HipA-like N-terminal domain; HipA-like C-terminal domain.
       0.490
AEE51802.1
COGs: COG1040 amidophosphoribosyltransferase; KEGG: phe:Phep_3856 phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; IMG reference gene:2504773339; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
   
    0.458
AEE48533.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: cpi:Cpin_1939 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; IMG reference gene:2504769980; PFAM: Prephenate dehydrogenase.
  
    0.433
AEE50863.1
Protein of unknown function DUF159; COGs: COG2135 conserved hypothetical protein; InterPro IPR003738; KEGG: mxa:MXAN_5161 hypothetical protein; PFAM: Protein of unknown function DUF159; SPTR: Putative uncharacterized protein; IMG reference gene:2504772374; PFAM: Uncharacterised ACR, COG2135; Belongs to the SOS response-associated peptidase family.
   
    0.415
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.414
AEE48714.1
parB-like partition protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: mtt:Ftrac_3754 ParB-like partition protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB-like partition protein; TIGRFAM: ParB-like partition protein; IMG reference gene:2504770167; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family.
  
  
 0.404
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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