Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE48416.1COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: cpi:Cpin_0936 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-strand binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504769862; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). (112 aa)    
Predicted Functional Partners:
AEE50821.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
  
 
0.905
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
 
 
 0.837
AEE49355.1
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR004365:IPR003141:IPR 004805; KEGG: chu:CHU_0094 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; IMG reference gene:2504770822; PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; TIGRFA [...]
   
 
 0.832
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.794
AEE51486.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 0.788
AEE48415.1
Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107:IPR002104; KEGG: ran:Riean_0325 integrase family protein; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Integrase family protein; IMG reference gene:2504769861; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; Belongs to the 'phage' integrase family.
 
   
 0.744
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
 
   0.710
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.709
rpsB
COGs: COG0052 Ribosomal protein S2; InterPro IPR005706:IPR001865; KEGG: cpi:Cpin_0882 ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid; IMG reference gene:2504772101; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
   
  0.708
rplJ
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
    0.697
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.