| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48514.1 | AEE48515.1 | Halhy_0605 | Halhy_0606 | KEGG: sli:Slin_4465 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769961; PFAM: Protein of unknown function (DUF2911). | KEGG: sli:Slin_2357 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769962. | 0.596 |
| AEE48514.1 | AEE48516.1 | Halhy_0605 | Halhy_0607 | KEGG: sli:Slin_4465 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769961; PFAM: Protein of unknown function (DUF2911). | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | 0.415 |
| AEE48515.1 | AEE48514.1 | Halhy_0606 | Halhy_0605 | KEGG: sli:Slin_2357 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769962. | KEGG: sli:Slin_4465 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769961; PFAM: Protein of unknown function (DUF2911). | 0.596 |
| AEE48515.1 | AEE48516.1 | Halhy_0606 | Halhy_0607 | KEGG: sli:Slin_2357 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769962. | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | 0.522 |
| AEE48516.1 | AEE48514.1 | Halhy_0607 | Halhy_0605 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | KEGG: sli:Slin_4465 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769961; PFAM: Protein of unknown function (DUF2911). | 0.415 |
| AEE48516.1 | AEE48515.1 | Halhy_0607 | Halhy_0606 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | KEGG: sli:Slin_2357 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769962. | 0.522 |
| AEE48516.1 | AEE49532.1 | Halhy_0607 | Halhy_1643 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transductio [...] | 0.676 |
| AEE48516.1 | AEE50547.1 | Halhy_0607 | Halhy_2679 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014:IPR013767:IPR003661:IPR003594; KEGG: phe:Phep_2493 PAS sensor protein; PFAM: ATP-binding region, ATPase-like; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; SPTR: Sensor histidine kinase; TIGRFAM: PAS; IMG reference gene:2504772050; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS [...] | 0.471 |
| AEE48516.1 | AEE51053.1 | Halhy_0607 | Halhy_3192 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: lby:Lbys_3178 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Sensor protein RprX; IMG reference gene:2504772572; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.419 |
| AEE48516.1 | AEE51190.1 | Halhy_0607 | Halhy_3331 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | Integral membrane sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003661:IPR003594; KEGG: fjo:Fjoh_3461 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Sensor protein RprX; IMG reference gene:2504772711; PFAM: Histidine kinase-, DNA gyrase B-, and HSP9 [...] | 0.482 |
| AEE48516.1 | AEE52172.1 | Halhy_0607 | Halhy_4328 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003661:IPR003594:IPR001789:IPR 008207:IPR000014:IPR001610; KEGG: sli:Slin_6270 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgro [...] | 0.699 |
| AEE48516.1 | AEE52899.1 | Halhy_0607 | Halhy_5073 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | 0.699 |
| AEE48516.1 | AEE53153.1 | Halhy_0607 | Halhy_5328 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575; KEGG: pub:SAR11_0680 NAD-dependent formate dehydrogenase subunit beta; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NAD-dependent formate dehydrogenase beta subunit; IMG reference gene:2504774726; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase [...] | 0.532 |
| AEE48516.1 | AEE53486.1 | Halhy_0607 | Halhy_5663 | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013656:IPR013767; KEGG: ppn:Palpr_2639 pas/pac sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; PAS fold; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response reg [...] | 0.885 |
| AEE49532.1 | AEE48516.1 | Halhy_1643 | Halhy_0607 | Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transductio [...] | Transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR019931; KEGG: dfe:Dfer_4900 putative two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; SPTR: Putative two component transcriptional regulator, winged helix family; TIGRFAM: LPXTG-motif cell wall anchor; IMG reference gene:2504769963; PFAM: Transcriptional regulatory protein, C terminal. | 0.676 |
| AEE49532.1 | AEE50547.1 | Halhy_1643 | Halhy_2679 | Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transductio [...] | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014:IPR013767:IPR003661:IPR003594; KEGG: phe:Phep_2493 PAS sensor protein; PFAM: ATP-binding region, ATPase-like; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; SPTR: Sensor histidine kinase; TIGRFAM: PAS; IMG reference gene:2504772050; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS [...] | 0.859 |
| AEE49532.1 | AEE51053.1 | Halhy_1643 | Halhy_3192 | Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transductio [...] | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: lby:Lbys_3178 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Sensor protein RprX; IMG reference gene:2504772572; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.453 |
| AEE49532.1 | AEE51190.1 | Halhy_1643 | Halhy_3331 | Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transductio [...] | Integral membrane sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003661:IPR003594; KEGG: fjo:Fjoh_3461 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Sensor protein RprX; IMG reference gene:2504772711; PFAM: Histidine kinase-, DNA gyrase B-, and HSP9 [...] | 0.437 |
| AEE49532.1 | AEE52172.1 | Halhy_1643 | Halhy_4328 | Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transductio [...] | COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003661:IPR003594:IPR001789:IPR 008207:IPR000014:IPR001610; KEGG: sli:Slin_6270 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgro [...] | 0.961 |
| AEE49532.1 | AEE52899.1 | Halhy_1643 | Halhy_5073 | Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR008207; KEGG: cts:Ctha_0019 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transductio [...] | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | 0.986 |
