Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE48544.1Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: dfe:Dfer_1279 two component transcriptional regulator, LytTR family; PFAM: Signal transduction response regulator, receiver region; LytTr DNA-binding region; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, LytTR family; IMG reference gene:2504769991; PFAM: Response regulator receiver domain; LytTr DNA-binding domain. (247 aa)    
Predicted Functional Partners:
AEE48543.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR011110:IPR011123:IPR010559:IPR003594; KEGG: cpi:Cpin_1400 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; Two component regulator three Y; Two component regulator propeller; ATP-binding region, ATPase-like; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504769990; PFAM: Histidine kinase; Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Two component regulator propeller.
 
   0.880
AEE52136.1
Histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR010559:IPR003594; KEGG: rbi:RB2501_03455 ATP-binding region, ATPase-like protein; PFAM: Signal transduction histidine kinase, internal region; ATP-binding region, ATPase-like; SPTR: ATP-binding region, ATPase-like protein; IMG reference gene:2504773678; PFAM: Histidine kinase.
 
  
 0.807
AEE48950.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: dfe:Dfer_1280 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504770412; PFAM: Histidine kinase.
 
   0.797
AEE49193.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559:IPR003594; KEGG: cpi:Cpin_1007 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; ATP-binding region, ATPase-like; SPTR: Sensor histidine kinase; IMG reference gene:2504770659; PFAM: Histidine kinase; 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
   0.795
AEE49228.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559:IPR003594; KEGG: cpi:Cpin_6624 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; ATP-binding region, ATPase-like; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504770694; PFAM: Histidine kinase.
 
   0.795
AEE52389.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR001440:IPR010559:IPR003594:IPR019734; KEGG: cpi:Cpin_6624 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; Tetratricopeptide TPR-1; ATP-binding region, ATPase-like; SMART: Tetratricopeptide repeat; SPTR: Possible sensor protein; IMG reference gene:2504773936; PFAM: Histidine kinase.
 
   0.792
AEE53964.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559:IPR003594; KEGG: sli:Slin_2907 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; ATP-binding region, ATPase-like; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504775544; PFAM: Histidine kinase.
 
   0.783
AEE49379.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: sli:Slin_4868 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504770847; PFAM: Histidine kinase.
  
   0.782
AEE47933.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: dfe:Dfer_4523 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504769369; PFAM: Histidine kinase.
 
   0.779
AEE48922.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: bth:BT_1458 putative two-component system sensor histidine kinase; PFAM: Signal transduction histidine kinase, internal region; SPTR: Putative two-component system sensor histidine kinase; IMG reference gene:2504770383; PFAM: Histidine kinase.
 
   0.778
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.