Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEE48613.1Cyclase family protein; COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: sli:Slin_1543 cyclase family protein; PFAM: Putative cyclase; SPTR: Cyclase family protein; IMG reference gene:2504770063; PFAM: Putative cyclase. (252 aa)    
Predicted Functional Partners:
AEE48614.1
Antibiotic biosynthesis monooxygenase; COGs: COG2329 Uncharacterized protein involved in biosynthesis of extracellular polysaccharides; InterPro IPR007138; KEGG: lch:Lcho_0826 antibiotic biosynthesis monooxygenase; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: Antibiotic biosynthesis monooxygenase; IMG reference gene:2504770064; PFAM: Antibiotic biosynthesis monooxygenase.
 
     0.817
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
  
  
 0.711
AEE48381.1
COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: sli:Slin_1557 amidohydrolase 2; PFAM: Amidohydrolase 2; SPTR: Amidohydrolase 2; IMG reference gene:2504769827; PFAM: Amidohydrolase.
 
     0.654
AEE53623.1
Protein of unknown function DUF849; COGs: COG3246 conserved hypothetical protein; InterPro IPR008567; KEGG: rbi:RB2501_11342 hypothetical protein; PFAM: Protein of unknown function DUF849, prokaryotic; SPTR: Putative uncharacterized protein; IMG reference gene:2504775198; PFAM: Prokaryotic protein of unknown function (DUF849).
 
  
 0.649
AEE48639.1
InterPro IPR013096; KEGG: sjp:SJA_C2-01010 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Putative uncharacterized protein; IMG reference gene:2504770089; PFAM: Cupin domain.
  
    0.615
AEE48373.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: sli:Slin_1560 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: AMP-dependent synthetase and ligase; IMG reference gene:2504769819; PFAM: AMP-binding enzyme.
 
     0.515
AEE48377.1
FAD dependent oxidoreductase; COGs: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; InterPro IPR006076; KEGG: sli:Slin_0336 monooxygenase FAD-binding protein; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase FAD-binding protein; IMG reference gene:2504769823; PFAM: FAD binding domain.
 
     0.505
AEE48378.1
KEGG: sli:Slin_1562 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769824; PFAM: Protein of unknown function (DUF3237); Belongs to the UPF0311 family.
 
     0.493
AEE48372.1
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: sli:Slin_1561 enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; SPTR: Enoyl-CoA hydratase/isomerase; IMG reference gene:2504769818; PFAM: Enoyl-CoA hydratase/isomerase family.
  
     0.449
AEE48374.1
KEGG: sli:Slin_1558 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504769820.
  
     0.447
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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