Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE48624.1Isoquinoline 1-oxidoreductase; COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR008274:IPR006311; KEGG: rbi:RB2501_01021 isoquinoline 1-oxidoreductase subunit beta; PFAM: Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; PRIAM: Isoquinoline 1-oxidoreductase; SPTR: Isoquinoline 1-oxidoreductase, beta subunit; IMG reference gene:2504770074; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase. (751 aa)    
Predicted Functional Partners:
AEE48625.1
Isoquinoline 1-oxidoreductase; COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: rbi:RB2501_01016 isoquinoline 1-oxidoreductase subunit alpha; PFAM: [2Fe-2S]-binding; Ferredoxin; PRIAM: Isoquinoline 1-oxidoreductase; SPTR: (2Fe-2S)-binding domain protein; IMG reference gene:2504770075; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain.
 
 0.924
AEE52980.1
Isoquinoline 1-oxidoreductase; COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: dfe:Dfer_0018 (2Fe-2S)-binding domain protein; PFAM: [2Fe-2S]-binding; Ferredoxin; PRIAM: Isoquinoline 1-oxidoreductase; SPTR: (2Fe-2S)-binding domain protein; IMG reference gene:2504774552; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain.
 
 0.844
AEE50339.1
Isoquinoline 1-oxidoreductase; COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: dfe:Dfer_3446 (2Fe-2S)-binding domain protein; PFAM: [2Fe-2S]-binding; Ferredoxin; PRIAM: Isoquinoline 1-oxidoreductase; SPTR: (2Fe-2S)-binding domain protein; IMG reference gene:2504771835; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain.
 
 0.843
AEE51628.1
Isoquinoline 1-oxidoreductase; COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: hoh:Hoch_0273 (2Fe-2S)-binding domain protein; PFAM: [2Fe-2S]-binding; Ferredoxin; PRIAM: Isoquinoline 1-oxidoreductase; SPTR: Isoquinoline 1-oxidoreductase, alpha subunit; IMG reference gene:2504773160; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain.
 
 0.820
AEE53031.1
Isoquinoline 1-oxidoreductase; COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: rsc:RCFBP_11442 isoquinoline 1-oxidoreductase (alpha subunit); PFAM: [2Fe-2S]-binding; Ferredoxin; PRIAM: Isoquinoline 1-oxidoreductase; SPTR: Aldehyde dehydrogenase subunit III; IMG reference gene:2504774603; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain.
 
 0.794
AEE50691.1
Carbon-monoxide dehydrogenase (acceptor); COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346:IPR005107; KEGG: tro:trd_1208 carbon monoxide dehydrogenase medium chain; PFAM: Molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein, C-terminal; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Molybdopterin dehydrogenase FAD-binding; IMG reference gene:2504772198; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain.
  
 
 0.559
AEE53110.1
Carbon-monoxide dehydrogenase (acceptor); COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346:IPR005107; KEGG: tro:trd_A0566 nicotine dehydrogenase chain A; PFAM: Molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein, C-terminal; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Nicotine dehydrogenase chain A; IMG reference gene:2504774683; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain.
  
 
 0.559
AEE49161.1
4-diphosphocytidyl-2C-methyl-D-erythritol synthase; COGs: COG2068 Uncharacterized MobA-related protein; KEGG: npu:Npun_F1862 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: Putative uncharacterized protein; IMG reference gene:2504770627; PFAM: Uncharacterized protein family UPF0007.
 
   
 0.501
AEE50689.1
Carbon-monoxide dehydrogenase (acceptor); COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: msv:Mesil_2696 (2Fe-2S)-binding domain protein; PFAM: [2Fe-2S]-binding; Ferredoxin; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: (2Fe-2S)-binding domain protein; IMG reference gene:2504772196; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain.
  
 
 0.431
AEE53111.1
Carbon-monoxide dehydrogenase (acceptor); COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: tro:trd_1206 [2Fe-2S] binding domain protein; PFAM: [2Fe-2S]-binding; Ferredoxin; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: [2Fe-2S] binding domain protein; IMG reference gene:2504774684; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain.
  
 
 0.431
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.