| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48355.1 | AEE48682.1 | Halhy_0444 | Halhy_0775 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | 0.429 |
| AEE48355.1 | AEE49884.1 | Halhy_0444 | Halhy_1999 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: cpi:Cpin_6916 type I citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: Citrate (Si)-synthase; IMG reference gene:2504771365; PFAM: Citrate synthase; TIGRFAM: citrate (Si)-synthase, eukaryotic; Belongs to the citrate synthase family. | 0.927 |
| AEE48355.1 | AEE51969.1 | Halhy_0444 | Halhy_4123 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | Phenylacetic acid degradation protein paaN; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR002539:IPR011966; KEGG: rmr:Rmar_1556 phenylacetic acid degradation protein PaaN; PFAM: MaoC-like dehydratase; Aldehyde dehydrogenase; PRIAM: Aldehyde dehydrogenase (NAD(+)); SPTR: NAD-dependent aldehyde dehydrogenases; TIGRFAM: Phenylacetic acid degradation protein paaN; IMG reference gene:2504773509; PFAM: MaoC like domain; Aldehyde dehydrogenase family; TIGRFAM: phenylacetic acid degradation protein paaN. | 0.557 |
| AEE48355.1 | AEE52829.1 | Halhy_0444 | Halhy_5001 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | COGs: COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase beta subunit; InterPro IPR004165:IPR012792:IPR012791; KEGG: sli:Slin_1533 3-oxoacid CoA-transferase, B subunit; PFAM: Coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, subunit B; 3-oxoacid CoA-transferase, subunit A; IMG reference gene:2504774396; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; 3-oxoacid CoA-transferase, A subunit. | 0.631 |
| AEE48355.1 | AEE54329.1 | Halhy_0444 | Halhy_6513 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...] | 0.954 |
| AEE48355.1 | icmF | Halhy_0444 | Halhy_2347 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | Methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.500 |
| AEE48628.1 | AEE48682.1 | Halhy_0720 | Halhy_0775 | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: hel:HELO_2421 acyl-CoA synthetase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: Acyl-CoA synthase; IMG reference gene:2504770078; PFAM: AMP-binding enzyme. | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | 0.403 |
| AEE48628.1 | AEE52829.1 | Halhy_0720 | Halhy_5001 | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: hel:HELO_2421 acyl-CoA synthetase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: Acyl-CoA synthase; IMG reference gene:2504770078; PFAM: AMP-binding enzyme. | COGs: COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase beta subunit; InterPro IPR004165:IPR012792:IPR012791; KEGG: sli:Slin_1533 3-oxoacid CoA-transferase, B subunit; PFAM: Coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, subunit B; 3-oxoacid CoA-transferase, subunit A; IMG reference gene:2504774396; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; 3-oxoacid CoA-transferase, A subunit. | 0.463 |
| AEE48682.1 | AEE48355.1 | Halhy_0775 | Halhy_0444 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | 0.429 |
| AEE48682.1 | AEE48628.1 | Halhy_0775 | Halhy_0720 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: hel:HELO_2421 acyl-CoA synthetase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: Acyl-CoA synthase; IMG reference gene:2504770078; PFAM: AMP-binding enzyme. | 0.403 |
| AEE48682.1 | AEE49157.1 | Halhy_0775 | Halhy_1262 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: mtt:Ftrac_3274 diamine N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Diamine N-acetyltransferase; IMG reference gene:2504770623; PFAM: Acetyltransferase (GNAT) family. | 0.426 |
| AEE48682.1 | AEE49884.1 | Halhy_0775 | Halhy_1999 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: cpi:Cpin_6916 type I citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: Citrate (Si)-synthase; IMG reference gene:2504771365; PFAM: Citrate synthase; TIGRFAM: citrate (Si)-synthase, eukaryotic; Belongs to the citrate synthase family. | 0.422 |
| AEE48682.1 | AEE50677.1 | Halhy_0775 | Halhy_2811 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | GCN5-related N-acetyltransferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR013650:IPR000182; KEGG: deh:cbdb_A1077 acetyl-CoA synthetase; PFAM: GCN5-related N-acetyltransferase; ATP-grasp fold, succinyl-CoA synthetase-type; CoA-binding; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504772183; PFAM: Acetyltransferase (GNAT) family. | 0.445 |
| AEE48682.1 | AEE51502.1 | Halhy_0775 | Halhy_3650 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | Thioester reductase domain protein; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR010080:IPR000873:IPR013120; KEGG: mav:MAV_4122 AMP-binding enzyme; PFAM: Male sterility, NAD-binding; AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: AMP-binding enzyme; TIGRFAM: Thioester reductase; IMG reference gene:2504773031; PFAM: Male sterility protein; AMP-binding enzyme; TIGRFAM: thioester reductase domain. | 0.475 |
| AEE48682.1 | AEE51969.1 | Halhy_0775 | Halhy_4123 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | Phenylacetic acid degradation protein paaN; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR002539:IPR011966; KEGG: rmr:Rmar_1556 phenylacetic acid degradation protein PaaN; PFAM: MaoC-like dehydratase; Aldehyde dehydrogenase; PRIAM: Aldehyde dehydrogenase (NAD(+)); SPTR: NAD-dependent aldehyde dehydrogenases; TIGRFAM: Phenylacetic acid degradation protein paaN; IMG reference gene:2504773509; PFAM: MaoC like domain; Aldehyde dehydrogenase family; TIGRFAM: phenylacetic acid degradation protein paaN. | 0.476 |
| AEE48682.1 | AEE52829.1 | Halhy_0775 | Halhy_5001 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | COGs: COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase beta subunit; InterPro IPR004165:IPR012792:IPR012791; KEGG: sli:Slin_1533 3-oxoacid CoA-transferase, B subunit; PFAM: Coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, subunit B; 3-oxoacid CoA-transferase, subunit A; IMG reference gene:2504774396; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; 3-oxoacid CoA-transferase, A subunit. | 0.439 |
| AEE48682.1 | AEE54329.1 | Halhy_0775 | Halhy_6513 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...] | 0.587 |
| AEE48682.1 | icmF | Halhy_0775 | Halhy_2347 | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | Methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.538 |
| AEE49157.1 | AEE48682.1 | Halhy_1262 | Halhy_0775 | GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: mtt:Ftrac_3274 diamine N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Diamine N-acetyltransferase; IMG reference gene:2504770623; PFAM: Acetyltransferase (GNAT) family. | Butyrate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: afu:AF1287 acetyl-CoA synthetase (acs-6); PFAM: AMP-dependent synthetase/ligase; PRIAM: Butyrate--CoA ligase; SPTR: Acetyl-CoA synthetase (Acs-6); IMG reference gene:2504770134; PFAM: AMP-binding enzyme. | 0.426 |
| AEE49884.1 | AEE48355.1 | Halhy_1999 | Halhy_0444 | COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: cpi:Cpin_6916 type I citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: Citrate (Si)-synthase; IMG reference gene:2504771365; PFAM: Citrate synthase; TIGRFAM: citrate (Si)-synthase, eukaryotic; Belongs to the citrate synthase family. | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | 0.927 |
