Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
AEE48691.1DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR011545:IPR001650:IPR014001; KEGG: sli:Slin_3330 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein; IMG reference gene:2504770143; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. (442 aa)    
Predicted Functional Partners:
AEE48080.1
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: cpi:Cpin_3971 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein; IMG reference gene:2504769519; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
  
  
 
0.918
AEE48071.1
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: sli:Slin_2449 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein; IMG reference gene:2504769510; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
  
  
 
0.909
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.700
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.643
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
  
 0.625
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
   
 0.622
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 0.583
rplJ
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 
 0.563
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
 
 0.557
rpmD
Ribosomal protein L30; InterPro IPR005996:IPR000517; KEGG: coc:Coch_1165 ribosomal protein L30; PFAM: Ribosomal protein L30p/L7e, conserved region; SPTR: 50S ribosomal protein L30; TIGRFAM: Ribosomal protein L30, bacterial-type; IMG reference gene:2504774152; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle.
   
 
 0.537
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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