Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEE48707.1COGs: COG2235 Arginine deiminase; InterPro IPR003198; KEGG: srm:SRM_00842 arginine deiminase; PFAM: Amidinotransferase; PRIAM: Arginine deiminase; SPTR: Amidinotransferase superfamily protein; IMG reference gene:2504770160; PFAM: Amidinotransferase. (416 aa)    
Predicted Functional Partners:
argH
COGs: COG0165 Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; InterPro IPR009049:IPR000362; KEGG: cpi:Cpin_6550 argininosuccinate lyase; PFAM: Fumarate lyase; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase; IMG reference gene:2504771407; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
     
 0.919
AEE49926.1
Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650; KEGG: dfe:Dfer_4431 peptidase dimerisation domain protein; PFAM: Peptidase M20; Peptidase M20, dimerisation; SPTR: Acetylornithine deacetylase; IMG reference gene:2504771408; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain.
 
  
 0.919
AEE52037.1
COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518; KEGG: fjo:Fjoh_3435 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; IMG reference gene:2504773577; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase.
     
 0.915
AEE52040.1
COGs: COG0078 Ornithine carbamoyltransferase; InterPro IPR006132:IPR006131; KEGG: dfe:Dfer_4418 aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: N-acetylornithine carbamoyltransferase; SPTR: Aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; IMG reference gene:2504773580; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domai [...]
 
  
 0.884
AEE49065.1
Orn/DAP/Arg decarboxylase 2; COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183; KEGG: cpi:Cpin_6223 Orn/DAP/Arg decarboxylase 2; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Orn/DAP/Arg decarboxylase 2; IMG reference gene:2504770528; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain.
     
  0.800
AEE48708.1
COGs: COG0824 thioesterase; InterPro IPR006683:IPR006684; KEGG: cpi:Cpin_2329 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase superfamily protein; TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; IMG reference gene:2504770161; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family.
       0.508
AEE48709.1
Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR004664:IPR017039; KEGG: phe:Phep_1844 ribonuclease BN; PFAM: Ribonuclease BN-related; SPTR: Ribonuclease BN; TIGRFAM: Ribonuclease BN; IMG reference gene:2504770162; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN).
       0.501
AEE48355.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
   
  
 0.494
AEE48706.1
Hypothetical protein; IMG reference gene:2504770159.
       0.459
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.403
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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