Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEE48748.1Citrate transporter; COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680:IPR006037; KEGG: zpr:ZPR_3645 transport protein; PFAM: Divalent ion symporter; Regulator of K+ conductance, C-terminal; SPTR: Transport protein; IMG reference gene:2504770203; PFAM: TrkA-C domain; Citrate transporter. (587 aa)    
Predicted Functional Partners:
AEE48747.1
Conserved hypothetical protein CHP00730; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: dma:DMR_23680 hypothetical protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00730; IMG reference gene:2504770202; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein; TIGR00730 family protein; Belongs to the LOG family.
       0.689
AEE48355.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
  
  
 0.563
cysQ
3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
 
   
 0.528
cysC
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
 0.522
AEE48746.1
Protein of unknown function DUF721; InterPro IPR007922; KEGG: zpr:ZPR_1452 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein; IMG reference gene:2504770201; PFAM: Protein of unknown function (DUF721).
       0.503
AEE51987.1
Na+/Ca+ antiporter, CaCA family; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: mrb:Mrub_2556 Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like; IMG reference gene:2504773527; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein.
 
    0.455
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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