| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48112.1 | AEE48355.1 | Halhy_0199 | Halhy_0444 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | 0.449 |
| AEE48112.1 | AEE49459.1 | Halhy_0199 | Halhy_1567 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.818 |
| AEE48112.1 | AEE49884.1 | Halhy_0199 | Halhy_1999 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: cpi:Cpin_6916 type I citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: Citrate (Si)-synthase; IMG reference gene:2504771365; PFAM: Citrate synthase; TIGRFAM: citrate (Si)-synthase, eukaryotic; Belongs to the citrate synthase family. | 0.827 |
| AEE48112.1 | AEE53948.1 | Halhy_0199 | Halhy_6126 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | Isocitrate dehydrogenase, NADP-dependent; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439:IPR001804; KEGG: bbe:BBR47_13900 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase, NADP-dependent; TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; IMG reference gene:2504775528; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type. | 0.847 |
| AEE48112.1 | AEE53974.1 | Halhy_0199 | Halhy_6152 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: phe:Phep_1507 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504775554; PFAM: Aminotransferase class I and II. | 0.918 |
| AEE48112.1 | fumC | Halhy_0199 | Halhy_1387 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.821 |
| AEE48112.1 | mdh | Halhy_0199 | Halhy_0859 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.926 |
| AEE48112.1 | mqo | Halhy_0199 | Halhy_4143 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | COGs: COG0579 dehydrogenase; HAMAP: Malate:quinone-oxidoreductase; InterPro IPR006231; KEGG: lbf:LBF_1037 malate:quinone oxidoreductase; PFAM: Malate:quinone-oxidoreductase; PRIAM: Malate dehydrogenase (acceptor); SPTR: Malate/quinone oxidoreductase; TIGRFAM: Malate:quinone-oxidoreductase; IMG reference gene:2504773529; PFAM: Malate:quinone oxidoreductase (Mqo); TIGRFAM: malate:quinone-oxidoreductase. | 0.808 |
| AEE48112.1 | pckG | Halhy_0199 | Halhy_2322 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.820 |
| AEE48355.1 | AEE48112.1 | Halhy_0444 | Halhy_0199 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | 0.449 |
| AEE48355.1 | AEE49459.1 | Halhy_0444 | Halhy_1567 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.957 |
| AEE48355.1 | AEE49884.1 | Halhy_0444 | Halhy_1999 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: cpi:Cpin_6916 type I citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: Citrate (Si)-synthase; IMG reference gene:2504771365; PFAM: Citrate synthase; TIGRFAM: citrate (Si)-synthase, eukaryotic; Belongs to the citrate synthase family. | 0.927 |
| AEE48355.1 | AEE53948.1 | Halhy_0444 | Halhy_6126 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | Isocitrate dehydrogenase, NADP-dependent; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439:IPR001804; KEGG: bbe:BBR47_13900 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase, NADP-dependent; TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; IMG reference gene:2504775528; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type. | 0.583 |
| AEE48355.1 | AEE53974.1 | Halhy_0444 | Halhy_6152 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: phe:Phep_1507 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504775554; PFAM: Aminotransferase class I and II. | 0.449 |
| AEE48355.1 | atpA | Halhy_0444 | Halhy_3259 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | 0.451 |
| AEE48355.1 | fumC | Halhy_0444 | Halhy_1387 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.967 |
| AEE48355.1 | mdh | Halhy_0444 | Halhy_0859 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.979 |
| AEE48355.1 | mqo | Halhy_0444 | Halhy_4143 | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | COGs: COG0579 dehydrogenase; HAMAP: Malate:quinone-oxidoreductase; InterPro IPR006231; KEGG: lbf:LBF_1037 malate:quinone oxidoreductase; PFAM: Malate:quinone-oxidoreductase; PRIAM: Malate dehydrogenase (acceptor); SPTR: Malate/quinone oxidoreductase; TIGRFAM: Malate:quinone-oxidoreductase; IMG reference gene:2504773529; PFAM: Malate:quinone oxidoreductase (Mqo); TIGRFAM: malate:quinone-oxidoreductase. | 0.935 |
| AEE49459.1 | AEE48112.1 | Halhy_1567 | Halhy_0199 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | 0.818 |
| AEE49459.1 | AEE48355.1 | Halhy_1567 | Halhy_0444 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. | 0.957 |
