Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE48818.1Band 7 protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: mtt:Ftrac_1605 SPFH domain, band 7 family protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Membrane protease subunit, SPFH domain/band 7 family protein; IMG reference gene:2504770277; PFAM: SPFH domain / Band 7 family. (296 aa)    
Predicted Functional Partners:
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.695
AEE48817.1
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR008250:IPR005834:IPR006068:IPR 001757; KEGG: atpase, p-type (transporting), had superfamily, subfamily IC; PFAM: ATPase, P-type, ATPase-associated region; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SPTR: ATPase, P-type (Transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference ge [...]
   
  0.582
AEE52705.1
OmpA/MotB domain protein; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
 
 0.477
AEE48819.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: rbi:RB2501_02820 two-component system response regulator; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two-component system response regulator; IMG reference gene:2504770278; PFAM: Response regulator receiver domain; Transcriptional regula [...]
  
    0.425
AEE48820.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: dfe:Dfer_2761 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SPTR: Two-component system sensor histidine kinase; IMG reference gene:2504770279; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase [...]
   
   0.415
AEE49932.1
AAA ATPase central domain protein; COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterPro IPR003593:IPR003959; KEGG: sus:Acid_2303 ATPase central domain-containing protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase, central domain protein; IMG reference gene:2504771414; PFAM: ATPase family associated with various cellular activities (AAA).
   
 
 0.401
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.