Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEE48821.1CBS domain containing protein; InterPro IPR000644; KEGG: mif:Metin_0071 putative signal transduction protein with CBS domains; PFAM: Cystathionine beta-synthase, core; SPTR: Putative signal transduction protein with CBS domains; IMG reference gene:2504770280; PFAM: CBS domain. (135 aa)    
Predicted Functional Partners:
AEE48822.1
COGs: COG0288 Carbonic anhydrase; InterPro IPR001765; KEGG: lbf:LBF_4256 carbonate dehydratase; PFAM: Carbonic anhydrase; SPTR: Putative beta-type carbonic anhydrase; IMG reference gene:2504770281; PFAM: Carbonic anhydrase.
       0.608
AEE48820.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: dfe:Dfer_2761 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SPTR: Two-component system sensor histidine kinase; IMG reference gene:2504770279; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase [...]
       0.539
AEE48819.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: rbi:RB2501_02820 two-component system response regulator; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two-component system response regulator; IMG reference gene:2504770278; PFAM: Response regulator receiver domain; Transcriptional regula [...]
       0.529
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.454
AEE48823.1
InterPro IPR019619; KEGG: sli:Slin_2451 protein of unknown function DUF2490; PFAM: Protein of unknown function DUF2490; SPTR: Putative uncharacterized protein; IMG reference gene:2504770282; PFAM: Protein of unknown function (DUF2490).
       0.446
AEE50984.1
COGs: COG0517 FOG: CBS domain; InterPro IPR000644; KEGG: rbi:RB2501_02745 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain protein; IMG reference gene:2504772502; PFAM: CBS domain.
  
     0.415
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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