Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (237 aa)    
Predicted Functional Partners:
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
 
 
 0.965
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
  
 0.932
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.912
AEE51196.1
RNA binding S1 domain protein; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029; KEGG: cpi:Cpin_6619 RNA binding S1 domain protein; PFAM: Ribosomal protein S1, RNA binding domain; SPTR: RNA binding S1 domain protein; IMG reference gene:2504772717; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
 
 
 0.902
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
  
    0.851
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
 
 0.828
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.789
AEE50663.1
Helicase domain-containing protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: pph:Ppha_1422 helicase domain protein; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase-like; IMG reference gene:2504772166; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
  
 
 0.786
rimM
Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
  
  
 0.772
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
 
 0.761
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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