| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48837.1 | AEE48838.1 | Halhy_0936 | Halhy_0937 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | KEGG: coc:Coch_1825 membrane protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770297. | 0.757 |
| AEE48837.1 | AEE48896.1 | Halhy_0936 | Halhy_0997 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | 0.869 |
| AEE48837.1 | AEE51463.1 | Halhy_0936 | Halhy_3611 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275:IPR005481:IPR005479:IPR005480; KEGG: phe:Phep_0124 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; IMG reference gene:2504772992; PFAM: Carba [...] | 0.975 |
| AEE48837.1 | AEE53250.1 | Halhy_0936 | Halhy_5425 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | Phosphoribosyltransferase; COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: cpi:Cpin_5885 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; IMG reference gene:2504774823; PFAM: Phosphoribosyl transferase domain. | 0.839 |
| AEE48837.1 | AEE53893.1 | Halhy_0936 | Halhy_6071 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR006680; KEGG: sli:Slin_5385 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Amidohydrolase; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504775473; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.926 |
| AEE48837.1 | AEE54318.1 | Halhy_0936 | Halhy_6502 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR011995:IPR001754; KEGG: pmz:HMPREF0659_A6727 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; IMG reference gene:2504775911; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2. | 0.813 |
| AEE48837.1 | carA | Halhy_0936 | Halhy_4776 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: phe:Phep_0705 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: Carbamoyl phosphate synthase, small subunit; IMG reference gene:2504774168; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosp [...] | 0.990 |
| AEE48837.1 | pyrB | Halhy_0936 | Halhy_0998 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: chu:CHU_0084 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504770358; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ [...] | 0.999 |
| AEE48837.1 | pyrD | Halhy_0936 | Halhy_3413 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.984 |
| AEE48837.1 | pyrE | Halhy_0936 | Halhy_6291 | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.859 |
| AEE48838.1 | AEE48837.1 | Halhy_0937 | Halhy_0936 | KEGG: coc:Coch_1825 membrane protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770297. | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.757 |
| AEE48896.1 | AEE48837.1 | Halhy_0997 | Halhy_0936 | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR004722; KEGG: dfe:Dfer_4467 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase, multifunctional complex type; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504770296; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.869 |
| AEE48896.1 | AEE51463.1 | Halhy_0997 | Halhy_3611 | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275:IPR005481:IPR005479:IPR005480; KEGG: phe:Phep_0124 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; IMG reference gene:2504772992; PFAM: Carba [...] | 0.813 |
| AEE48896.1 | AEE53250.1 | Halhy_0997 | Halhy_5425 | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | Phosphoribosyltransferase; COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: cpi:Cpin_5885 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; IMG reference gene:2504774823; PFAM: Phosphoribosyl transferase domain. | 0.927 |
| AEE48896.1 | AEE53893.1 | Halhy_0997 | Halhy_6071 | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | Dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR006680; KEGG: sli:Slin_5385 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: Allantoinase; SPTR: Amidohydrolase; TIGRFAM: Dihydroorotase multifunctional complex type; IMG reference gene:2504775473; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type. | 0.609 |
| AEE48896.1 | AEE54318.1 | Halhy_0997 | Halhy_6502 | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR011995:IPR001754; KEGG: pmz:HMPREF0659_A6727 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; IMG reference gene:2504775911; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2. | 0.972 |
| AEE48896.1 | carA | Halhy_0997 | Halhy_4776 | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: phe:Phep_0705 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: Carbamoyl phosphate synthase, small subunit; IMG reference gene:2504774168; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosp [...] | 0.734 |
| AEE48896.1 | pyrB | Halhy_0997 | Halhy_0998 | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: chu:CHU_0084 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504770358; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ [...] | 0.992 |
| AEE48896.1 | pyrD | Halhy_0997 | Halhy_3413 | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.617 |
| AEE48896.1 | pyrE | Halhy_0997 | Halhy_6291 | COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.749 |