Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEE48870.1Cyclase family protein; COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: rbi:RB2501_10877 polyketide cyclase; PFAM: Putative cyclase; SPTR: Hypothetical polyketide cyclase; IMG reference gene:2504770329; PFAM: Putative cyclase. (325 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
  
 0.743
AEE48871.1
Protein of unknown function DUF606; COGs: COG3238 conserved hypothetical protein; InterPro IPR006750; KEGG: aar:Acear_1207 protein of unknown function DUF606; PFAM: Protein of unknown function DUF606; SPTR: Putative uncharacterized protein; IMG reference gene:2504770330; PFAM: Protein of unknown function, DUF606.
       0.662
AEE48639.1
InterPro IPR013096; KEGG: sjp:SJA_C2-01010 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Putative uncharacterized protein; IMG reference gene:2504770089; PFAM: Cupin domain.
  
    0.615
AEE53623.1
Protein of unknown function DUF849; COGs: COG3246 conserved hypothetical protein; InterPro IPR008567; KEGG: rbi:RB2501_11342 hypothetical protein; PFAM: Protein of unknown function DUF849, prokaryotic; SPTR: Putative uncharacterized protein; IMG reference gene:2504775198; PFAM: Prokaryotic protein of unknown function (DUF849).
  
  
 0.567
AEE48869.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: cpi:Cpin_5018 putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding; SPTR: Putative uncharacterized protein; IMG reference gene:2504770328; PFAM: Cyclic nucleotide-binding domain.
  
    0.558
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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