Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEE48871.1Protein of unknown function DUF606; COGs: COG3238 conserved hypothetical protein; InterPro IPR006750; KEGG: aar:Acear_1207 protein of unknown function DUF606; PFAM: Protein of unknown function DUF606; SPTR: Putative uncharacterized protein; IMG reference gene:2504770330; PFAM: Protein of unknown function, DUF606. (147 aa)    
Predicted Functional Partners:
AEE48870.1
Cyclase family protein; COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: rbi:RB2501_10877 polyketide cyclase; PFAM: Putative cyclase; SPTR: Hypothetical polyketide cyclase; IMG reference gene:2504770329; PFAM: Putative cyclase.
       0.662
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
    0.562
AEE54318.1
COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR011995:IPR001754; KEGG: pmz:HMPREF0659_A6727 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; IMG reference gene:2504775911; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2.
  
    0.559
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
    0.546
AEE48869.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: cpi:Cpin_5018 putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding; SPTR: Putative uncharacterized protein; IMG reference gene:2504770328; PFAM: Cyclic nucleotide-binding domain.
       0.478
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: chu:CHU_0084 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504770358; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ [...]
  
    0.417
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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