Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE48896.1COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: phe:Phep_1174 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504770357; PFAM: Phosphoribosyl transferase domain. (185 aa)    
Predicted Functional Partners:
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: chu:CHU_0084 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504770358; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ [...]
 
 
 0.992
AEE54318.1
COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR011995:IPR001754; KEGG: pmz:HMPREF0659_A6727 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase, core; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, subfamily 2, core; IMG reference gene:2504775911; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2.
  
 
 0.972
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.930
AEE53250.1
Phosphoribosyltransferase; COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: cpi:Cpin_5885 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; IMG reference gene:2504774823; PFAM: Phosphoribosyl transferase domain.
  
  
 
0.927
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.914
AEE52085.1
COGs: COG0035 Uracil phosphoribosyltransferase; KEGG: ran:Riean_1525 uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; IMG reference gene:2504773626; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase.
     
 0.913
AEE53771.1
COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: mtt:Ftrac_2535 phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase/uridine kinase; PRIAM: Uridine kinase; SPTR: Uridine kinase; IMG reference gene:2504775348; PFAM: Phosphoribulokinase / Uridine kinase family.
     
 0.913
AEE48171.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    
  0.903
AEE48201.1
Purine or other phosphorylase family 1; COGs: COG2820 Uridine phosphorylase; InterPro IPR000845; KEGG: cpi:Cpin_4693 purine or other phosphorylase family 1; PFAM: Nucleoside phosphorylase; SPTR: Purine nucleoside phosphorylase II; IMG reference gene:2504769644; PFAM: Phosphorylase superfamily.
    
 0.902
psuG
Pseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
     
 0.901
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (18%) [HD]