Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEE48911.1COGs: COG5635 NTPase (NACHT family); KEGG: ckr:CKR_1736 hypothetical protein; SPTR: Putative signal transduction protein with Nacht domain; IMG reference gene:2504770372; PFAM: NACHT domain. (592 aa)    
Predicted Functional Partners:
cobB
COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent deacetylase; InterPro IPR003000; KEGG: zpr:ZPR_2106 NAD-dependent histone deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Putative uncharacterized protein; IMG reference gene:2504775815; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
   
   0.559
AEE51225.1
KEGG: dfe:Dfer_1264 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772747.
  
     0.503
AEE54249.1
Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: cpi:Cpin_6708 Appr-1-p processing domain protein; PFAM: Appr-1-p processing; SMART: Appr-1-p processing; SPTR: Appr-1-p processing domain protein; IMG reference gene:2504775839; PFAM: Macro domain.
  
     0.482
AEE48584.1
KEGG: gau:GAU_3477 hypothetical membrane protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770034.
  
     0.469
AEE49434.1
Methyltransferase type 11; InterPro IPR013216; KEGG: chu:CHU_1869 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Putative uncharacterized protein; IMG reference gene:2504770903; PFAM: Methyltransferase domain.
  
     0.462
AEE49436.1
KEGG: cpi:Cpin_4431 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770905.
  
     0.446
AEE52806.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: chu:CHU_0226 cyclic nucleotide binding regulatory protein; PFAM: Cyclic nucleotide-binding; SPTR: Cyclic nucleotide binding regulatory protein; IMG reference gene:2504774373; PFAM: Cyclic nucleotide-binding domain.
  
     0.440
AEE48566.1
Hypothetical protein; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: tye:THEYE_A1494 ribonuclease Z; SPTR: Metal-dependent hydrolases of the beta-lactamase superfamily III protein; IMG reference gene:2504770014.
  
     0.438
AEE49435.1
KEGG: chu:CHU_1868 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504770904; PFAM: Uncharacterized conserved protein (COG2071).
  
     0.436
AEE52804.1
KEGG: sli:Slin_2878 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504774371.
  
     0.408
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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