close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE48926.1Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: cpi:Cpin_1844 two component transcriptional regulator, LytTR family; PFAM: LytTr DNA-binding region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Two-component system response regulator protein; IMG reference gene:2504770388; PFAM: Response regulator receiver domain; LytTr DNA-binding domain. (237 aa)    
Predicted Functional Partners:
AEE52136.1
Histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR010559:IPR003594; KEGG: rbi:RB2501_03455 ATP-binding region, ATPase-like protein; PFAM: Signal transduction histidine kinase, internal region; ATP-binding region, ATPase-like; SPTR: ATP-binding region, ATPase-like protein; IMG reference gene:2504773678; PFAM: Histidine kinase.
 
  
 0.808
AEE48922.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: bth:BT_1458 putative two-component system sensor histidine kinase; PFAM: Signal transduction histidine kinase, internal region; SPTR: Putative two-component system sensor histidine kinase; IMG reference gene:2504770383; PFAM: Histidine kinase.
  
   0.807
AEE49039.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: dfe:Dfer_0598 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504770502; PFAM: Histidine kinase.
  
   0.807
AEE52696.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: dfe:Dfer_4523 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504774261; PFAM: Histidine kinase.
  
   0.807
AEE52789.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: lby:Lbys_0295 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; SPTR: Putative two-component system sensor protein, without kinase domain; IMG reference gene:2504774356; PFAM: Histidine kinase.
  
   0.807
AEE47933.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: dfe:Dfer_4523 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; SPTR: Signal transduction histidine kinase, LytS; IMG reference gene:2504769369; PFAM: Histidine kinase.
  
   0.806
AEE47991.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: dfe:Dfer_5361 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; SPTR: Putative two-component system sensor but no kinase domain; IMG reference gene:2504769428; PFAM: Histidine kinase.
  
   0.806
AEE51489.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: gau:GAU_3254 two-component histidine kinase; PFAM: Signal transduction histidine kinase, internal region; SPTR: Two-component histidine kinase; IMG reference gene:2504773018; PFAM: Histidine kinase.
  
   0.806
AEE48139.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: dfe:Dfer_4523 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; SPTR: Putative two component system, sensor protein; IMG reference gene:2504769578; PFAM: Histidine kinase.
  
   0.805
AEE48985.1
Putative signal transduction histidine kinase; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR010559; KEGG: fbc:FB2170_01437 putative two-component system sensor protein, without kinase domain; PFAM: Signal transduction histidine kinase, internal region; SPTR: Putative two component system, sensor protein; IMG reference gene:2504770448; PFAM: Histidine kinase.
  
   0.805
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.