| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48981.1 | AEE50531.1 | Halhy_1083 | Halhy_2662 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | 0.985 |
| AEE48981.1 | AEE52827.1 | Halhy_1083 | Halhy_4999 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | 3-carboxy-cis,cis-muconate cycloisomerase; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362:IPR019468:IPR012789; KEGG: avn:Avin_38190 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; PRIAM: 3-carboxy-cis,cis-muconate cycloisomerase; SPTR: 3-carboxy-cis,cis-muconate cycloisomerase; TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; IMG reference gene:2504774394; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase. | 0.958 |
| AEE48981.1 | AEE53216.1 | Halhy_1083 | Halhy_5391 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR000362:IPR013539; KEGG: coc:Coch_1238 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal; Fumarate lyase; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504774789; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.975 |
| AEE48981.1 | purC | Halhy_1083 | Halhy_6242 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; InterPro IPR001636; KEGG: chu:CHU_1912 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; IMG reference gene:2504775649; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.996 |
| AEE48981.1 | purD | Halhy_1083 | Halhy_1988 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR000115:IPR020562:IPR020561:IPR020560; KEGG: fjo:Fjoh_1041 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; IMG reference gene:2504771354; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphori [...] | 0.968 |
| AEE48981.1 | purK | Halhy_1083 | Halhy_6070 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.992 |
| AEE48981.1 | purL | Halhy_1083 | Halhy_5196 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.993 |
| AEE48981.1 | purN | Halhy_1083 | Halhy_3500 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.962 |
| AEE48981.1 | purQ | Halhy_1083 | Halhy_4319 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.993 |
| AEE48981.1 | purS | Halhy_1083 | Halhy_2946 | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.993 |
| AEE50531.1 | AEE48981.1 | Halhy_2662 | Halhy_1083 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | AIR synthase related protein domain protein; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: ppn:Palpr_1285 phosphoribosylformylglycinamidine cyclO-ligase; PFAM: AIR synthase related protein, C-terminal; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504770444; PFAM: AIR synthase related protein, C-terminal domain. | 0.985 |
| AEE50531.1 | AEE52827.1 | Halhy_2662 | Halhy_4999 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | 3-carboxy-cis,cis-muconate cycloisomerase; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362:IPR019468:IPR012789; KEGG: avn:Avin_38190 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; PRIAM: 3-carboxy-cis,cis-muconate cycloisomerase; SPTR: 3-carboxy-cis,cis-muconate cycloisomerase; TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; IMG reference gene:2504774394; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase. | 0.959 |
| AEE50531.1 | AEE53216.1 | Halhy_2662 | Halhy_5391 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR000362:IPR013539; KEGG: coc:Coch_1238 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal; Fumarate lyase; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504774789; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.973 |
| AEE50531.1 | purC | Halhy_2662 | Halhy_6242 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; InterPro IPR001636; KEGG: chu:CHU_1912 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; IMG reference gene:2504775649; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.979 |
| AEE50531.1 | purD | Halhy_2662 | Halhy_1988 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR000115:IPR020562:IPR020561:IPR020560; KEGG: fjo:Fjoh_1041 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; IMG reference gene:2504771354; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphori [...] | 0.998 |
| AEE50531.1 | purK | Halhy_2662 | Halhy_6070 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.990 |
| AEE50531.1 | purL | Halhy_2662 | Halhy_5196 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.940 |
| AEE50531.1 | purN | Halhy_2662 | Halhy_3500 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.964 |
| AEE50531.1 | purQ | Halhy_2662 | Halhy_4319 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.993 |
| AEE50531.1 | purS | Halhy_2662 | Halhy_2946 | Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: rbi:RB2501_07515 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; IMG reference gene:2504772033; PFAM: Glutamine amidotransferases class-II. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.923 |
