STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE49848.1HtrA2 peptidase; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254; KEGG: sli:Slin_2676 HtrA2 peptidase; PFAM: Peptidase S1/S6, chymotrypsin/Hap; PDZ/DHR/GLGF; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF; SPTR: HtrA2 peptidase; IMG reference gene:2504771324; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF). (331 aa)    
Predicted Functional Partners:
AEE49849.1
Rhodanese-like protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: rbi:RB2501_02165 rhodanese-like domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese-like domain protein; IMG reference gene:2504771325; PFAM: Rhodanese-like domain.
  
    0.512
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.491
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
   0.443
AEE49932.1
AAA ATPase central domain protein; COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterPro IPR003593:IPR003959; KEGG: sus:Acid_2303 ATPase central domain-containing protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase, central domain protein; IMG reference gene:2504771414; PFAM: ATPase family associated with various cellular activities (AAA).
    
 0.434
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
 
 
   0.424
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.