Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE49860.1Oxidoreductase alpha (molybdopterin) subunit; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006656:IPR006657:IPR010046; KEGG: cpi:Cpin_4072 oxidoreductase alpha (molybdopterin) subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Oxidoreductase alpha (Molybdopterin) subunit; TIGRFAM: Oxidoreductase alpha (molybdopterin) subunit; IMG reference gene:2504771336; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: oxidoreductase alpha (molybdopterin) [...] (803 aa)    
Predicted Functional Partners:
AEE53153.1
NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575; KEGG: pub:SAR11_0680 NAD-dependent formate dehydrogenase subunit beta; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NAD-dependent formate dehydrogenase beta subunit; IMG reference gene:2504774726; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase [...]
  
 
 0.897
AEE52700.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR006311:IPR001450; KEGG: mtt:Ftrac_3687 quinol:cytochrome c oxidoreductase iron-sulfur protein precursor; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Quinol:cytochrome c oxidoreductase iron-sulfur protein; IMG reference gene:2504774265.
  
 
 0.868
AEE49861.1
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.855
fdhD
Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.842
AEE52701.1
COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: cpi:Cpin_0527 polysulphide reductase NrfD; PFAM: Polysulphide reductase, NrfD; SPTR: Polysulphide reductase NrfD; IMG reference gene:2504774266; PFAM: Polysulphide reductase, NrfD.
  
 
 0.835
AEE54138.1
KEGG: net:Neut_2463 cytochrome c, class I; SPTR: Cytochrome c, class I; IMG reference gene:2504775727; PFAM: Cytochrome c.
  
 
 0.776
AEE49862.1
KEGG: fbc:FB2170_02290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771338; PFAM: Putative esterase.
       0.661
AEE49859.1
COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: sli:Slin_2809 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdopterin cofactor biosynthesis MoaC region; IMG reference gene:2504771335; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
 
   
 0.652
AEE47924.1
COGs: COG3278 Cbb3-type cytochrome oxidase subunit 1; InterPro IPR000883:IPR003468:IPR004677; KEGG: mtt:Ftrac_1616 cytochrome c oxidase, cbb3-type, subunit I; PFAM: Cytochrome C oxidase, monohaem subunit/FixO; Cytochrome c oxidase, subunit I; PRIAM: Cytochrome-c oxidase; SPTR: Cytochrome c oxidase, cbb3-type; TIGRFAM: Cytochrome c oxidase cbb3-type, subunit I; Cytochrome C oxidase, monohaem subunit/FixO; IMG reference gene:2504769359; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; [...]
  
  
 0.626
AEE54317.1
InterPro IPR017941; KEGG: sli:Slin_1751 Rieske (2Fe-2S) iron-sulphur domain protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske (2Fe-2S) iron-sulfur domain protein; IMG reference gene:2504775910; PFAM: Rieske [2Fe-2S] domain.
   
 
 0.585
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.