| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48572.1 | AEE49861.1 | Halhy_0664 | Halhy_1976 | Adenylate/guanylate cyclase with TPR repeats; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterProIPR003018:IPR013656:IPR001054:IPR013105:IPR 000014; KEGG: dsa:Desal_0985 adenylate/guanylate cyclase with GAF and PAS/PAC sensors; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS fold-4; Tetratricopeptide TPR2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS; SPTR: Adenylate/guanylate cyclase with GAF and PAS/PAC sensors; TIGRFAM: PAS; IMG reference gene:2504770022; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; [...] | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.824 |
| AEE48572.1 | AEE54242.1 | Halhy_0664 | Halhy_6424 | Adenylate/guanylate cyclase with TPR repeats; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterProIPR003018:IPR013656:IPR001054:IPR013105:IPR 000014; KEGG: dsa:Desal_0985 adenylate/guanylate cyclase with GAF and PAS/PAC sensors; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS fold-4; Tetratricopeptide TPR2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS; SPTR: Adenylate/guanylate cyclase with GAF and PAS/PAC sensors; TIGRFAM: PAS; IMG reference gene:2504770022; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; [...] | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: dev:DhcVS_971 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; IMG reference gene:2504775832; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. | 0.803 |
| AEE48572.1 | folE | Halhy_0664 | Halhy_0838 | Adenylate/guanylate cyclase with TPR repeats; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterProIPR003018:IPR013656:IPR001054:IPR013105:IPR 000014; KEGG: dsa:Desal_0985 adenylate/guanylate cyclase with GAF and PAS/PAC sensors; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS fold-4; Tetratricopeptide TPR2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS; SPTR: Adenylate/guanylate cyclase with GAF and PAS/PAC sensors; TIGRFAM: PAS; IMG reference gene:2504770022; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; [...] | COGs: COG0302 GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; InterPro IPR001474:IPR020602; KEGG: cts:Ctha_0487 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1 2; TIGRFAM: GTP cyclohydrolase I; IMG reference gene:2504770198; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.808 |
| AEE48572.1 | ribA | Halhy_0664 | Halhy_4808 | Adenylate/guanylate cyclase with TPR repeats; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterProIPR003018:IPR013656:IPR001054:IPR013105:IPR 000014; KEGG: dsa:Desal_0985 adenylate/guanylate cyclase with GAF and PAS/PAC sensors; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS fold-4; Tetratricopeptide TPR2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS; SPTR: Adenylate/guanylate cyclase with GAF and PAS/PAC sensors; TIGRFAM: PAS; IMG reference gene:2504770022; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; [...] | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.803 |
| AEE48572.1 | ribB | Halhy_0664 | Halhy_5567 | Adenylate/guanylate cyclase with TPR repeats; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterProIPR003018:IPR013656:IPR001054:IPR013105:IPR 000014; KEGG: dsa:Desal_0985 adenylate/guanylate cyclase with GAF and PAS/PAC sensors; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS fold-4; Tetratricopeptide TPR2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS; SPTR: Adenylate/guanylate cyclase with GAF and PAS/PAC sensors; TIGRFAM: PAS; IMG reference gene:2504770022; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; [...] | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.820 |
| AEE49859.1 | AEE49860.1 | Halhy_1974 | Halhy_1975 | COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: sli:Slin_2809 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdopterin cofactor biosynthesis MoaC region; IMG reference gene:2504771335; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC. | Oxidoreductase alpha (molybdopterin) subunit; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006656:IPR006657:IPR010046; KEGG: cpi:Cpin_4072 oxidoreductase alpha (molybdopterin) subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Oxidoreductase alpha (Molybdopterin) subunit; TIGRFAM: Oxidoreductase alpha (molybdopterin) subunit; IMG reference gene:2504771336; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: oxidoreductase alpha (molybdopterin) [...] | 0.652 |
| AEE49859.1 | AEE49861.1 | Halhy_1974 | Halhy_1976 | COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: sli:Slin_2809 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdopterin cofactor biosynthesis MoaC region; IMG reference gene:2504771335; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.999 |
| AEE49859.1 | AEE50009.1 | Halhy_1974 | Halhy_2124 | COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: sli:Slin_2809 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdopterin cofactor biosynthesis MoaC region; IMG reference gene:2504771335; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC. | thiamineS protein; InterPro IPR003749; KEGG: zpr:ZPR_2976 hypothetical protein; PFAM: ThiamineS; SPTR: Molybdopterin converting factor, subunit 1; IMG reference gene:2504771491; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal. | 0.962 |
| AEE49859.1 | AEE51904.1 | Halhy_1974 | Halhy_4056 | COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: sli:Slin_2809 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdopterin cofactor biosynthesis MoaC region; IMG reference gene:2504771335; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC. | Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: cpi:Cpin_0207 molybdopterin biosynthesis MoaE protein; PFAM: Molybdopterin biosynthesis MoaE; SPTR: Molybdopterin converting factor, subunit 2; IMG reference gene:2504773442; PFAM: MoaE protein. | 0.999 |
| AEE49859.1 | AEE54183.1 | Halhy_1974 | Halhy_6364 | COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: sli:Slin_2809 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdopterin cofactor biosynthesis MoaC region; IMG reference gene:2504771335; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.876 |
| AEE49860.1 | AEE49859.1 | Halhy_1975 | Halhy_1974 | Oxidoreductase alpha (molybdopterin) subunit; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006656:IPR006657:IPR010046; KEGG: cpi:Cpin_4072 oxidoreductase alpha (molybdopterin) subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Oxidoreductase alpha (Molybdopterin) subunit; TIGRFAM: Oxidoreductase alpha (molybdopterin) subunit; IMG reference gene:2504771336; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: oxidoreductase alpha (molybdopterin) [...] | COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: sli:Slin_2809 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdopterin cofactor biosynthesis MoaC region; IMG reference gene:2504771335; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC. | 0.652 |
| AEE49860.1 | AEE49861.1 | Halhy_1975 | Halhy_1976 | Oxidoreductase alpha (molybdopterin) subunit; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006656:IPR006657:IPR010046; KEGG: cpi:Cpin_4072 oxidoreductase alpha (molybdopterin) subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Oxidoreductase alpha (Molybdopterin) subunit; TIGRFAM: Oxidoreductase alpha (molybdopterin) subunit; IMG reference gene:2504771336; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: oxidoreductase alpha (molybdopterin) [...] | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.855 |
| AEE49860.1 | AEE54183.1 | Halhy_1975 | Halhy_6364 | Oxidoreductase alpha (molybdopterin) subunit; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006656:IPR006657:IPR010046; KEGG: cpi:Cpin_4072 oxidoreductase alpha (molybdopterin) subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Oxidoreductase alpha (Molybdopterin) subunit; TIGRFAM: Oxidoreductase alpha (molybdopterin) subunit; IMG reference gene:2504771336; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: oxidoreductase alpha (molybdopterin) [...] | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.506 |
| AEE49861.1 | AEE48572.1 | Halhy_1976 | Halhy_0664 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Adenylate/guanylate cyclase with TPR repeats; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterProIPR003018:IPR013656:IPR001054:IPR013105:IPR 000014; KEGG: dsa:Desal_0985 adenylate/guanylate cyclase with GAF and PAS/PAC sensors; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS fold-4; Tetratricopeptide TPR2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS; SPTR: Adenylate/guanylate cyclase with GAF and PAS/PAC sensors; TIGRFAM: PAS; IMG reference gene:2504770022; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; [...] | 0.824 |
| AEE49861.1 | AEE49859.1 | Halhy_1976 | Halhy_1974 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: sli:Slin_2809 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdopterin cofactor biosynthesis MoaC region; IMG reference gene:2504771335; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC. | 0.999 |
| AEE49861.1 | AEE49860.1 | Halhy_1976 | Halhy_1975 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Oxidoreductase alpha (molybdopterin) subunit; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006656:IPR006657:IPR010046; KEGG: cpi:Cpin_4072 oxidoreductase alpha (molybdopterin) subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Oxidoreductase alpha (Molybdopterin) subunit; TIGRFAM: Oxidoreductase alpha (molybdopterin) subunit; IMG reference gene:2504771336; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: oxidoreductase alpha (molybdopterin) [...] | 0.855 |
| AEE49861.1 | AEE50009.1 | Halhy_1976 | Halhy_2124 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | thiamineS protein; InterPro IPR003749; KEGG: zpr:ZPR_2976 hypothetical protein; PFAM: ThiamineS; SPTR: Molybdopterin converting factor, subunit 1; IMG reference gene:2504771491; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal. | 0.886 |
| AEE49861.1 | AEE51904.1 | Halhy_1976 | Halhy_4056 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: cpi:Cpin_0207 molybdopterin biosynthesis MoaE protein; PFAM: Molybdopterin biosynthesis MoaE; SPTR: Molybdopterin converting factor, subunit 2; IMG reference gene:2504773442; PFAM: MoaE protein. | 0.910 |
| AEE49861.1 | AEE54183.1 | Halhy_1976 | Halhy_6364 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.909 |
| AEE49861.1 | AEE54242.1 | Halhy_1976 | Halhy_6424 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: dev:DhcVS_971 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; IMG reference gene:2504775832; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. | 0.900 |
