Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (358 aa)    
Predicted Functional Partners:
AEE54155.1
protein-(glutamine-N5) methyltransferase, release factor-specific; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR004556:IPR019874:IPR007848; KEGG: cpi:Cpin_2220 modification methylase, HemK family; PFAM: Methyltransferase small; SPTR: Modification methylase, HemK family; TIGRFAM: Protein-(glutamine-N5) methyltransferase, release factor-specific; Modification methylase HemK; IMG reference gene:2504775744; PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; protein-(glutamine-N5) methyltransferase, release factor-specific.
 
 
 0.987
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 0.970
rpmA
COGs: COG0211 Ribosomal protein L27; HAMAP: Ribosomal protein L27; InterPro IPR001684; KEGG: bth:BT_4313 50S ribosomal protein L27; PFAM: Ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: Ribosomal protein L27; IMG reference gene:2504770871; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
 
 0.969
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
 
 0.962
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 0.945
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 0.945
rplP
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
 
 0.944
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
 
 0.943
rpsB
COGs: COG0052 Ribosomal protein S2; InterPro IPR005706:IPR001865; KEGG: cpi:Cpin_0882 ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid; IMG reference gene:2504772101; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
 
 0.941
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
 0.941
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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