STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE49903.1COGs: COG3508 Homogentisate 1 2-dioxygenase; InterPro IPR005708; KEGG: lby:Lbys_3502 homogentisate 12-dioxygenase; PFAM: Homogentisate 1,2-dioxygenase; SPTR: Homogentisate 12-dioxygenase; IMG reference gene:2504771384; PFAM: homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase. (385 aa)    
Predicted Functional Partners:
AEE53348.1
COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR005956:IPR004360; KEGG: lby:Lbys_3501 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; IMG reference gene:2504774921; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase.
 
 0.995
AEE49904.1
Fumarylacetoacetase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR015377:IPR002529:IPR005959; KEGG: cti:RALTA_B1480 fumarylacetoacetase (fumarylacetoacetate hydrolase); PFAM: Fumarylacetoacetase, N-terminal; Fumarylacetoacetase, C-terminal-like; PRIAM: Fumarylacetoacetase; SPTR: Fumarylacetoacetase; TIGRFAM: Fumarylacetoacetase; IMG reference gene:2504771385; PFAM: Domain of unknown function (DUF1969); Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: fumarylacetoacetase.
 
  
 0.950
AEE52213.1
InterPro IPR010839; KEGG: sli:Slin_4147 protein of unknown function DUF1446; PFAM: Protein of unknown function DUF1446; SPTR: Putative uncharacterized protein; IMG reference gene:2504773756; PFAM: Protein of unknown function (DUF1446).
  
 
 0.793
AEE49905.1
COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: mtt:Ftrac_3079 flavin reductase domain protein fmn-binding protein; PFAM: Flavin reductase-like, FMN-binding; SPTR: Flavin reductase domain protein FMN-binding protein; IMG reference gene:2504771386; PFAM: Flavin reductase like domain.
 
   
 0.729
AEE49304.1
Ureidoglycolate lyase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: lby:Lbys_1938 ureidoglycolate lyase; PFAM: Fumarylacetoacetase, C-terminal-like; PRIAM: Ureidoglycolate lyase; SPTR: Ureidoglycolate lyase; IMG reference gene:2504770770; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
  
  
 0.676
AEE52317.1
Fumarylacetoacetate (FAA) hydrolase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: cpi:Cpin_1536 fumarylacetoacetate (FAA) hydrolase; PFAM: Fumarylacetoacetase, C-terminal-like; SPTR: Fumarylacetoacetate hydrolase; IMG reference gene:2504773863; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
  
  
 0.676
AEE50981.1
Transcriptional coactivator/pterin dehydratase; COGs: COG2154 Pterin-4a-carbinolamine dehydratase; InterPro IPR001533; KEGG: cpi:Cpin_1008 transcriptional coactivator/pterin dehydratase; PFAM: Transcriptional coactivator/pterin dehydratase; SPTR: Transcriptional coactivator/pterin dehydratase; IMG reference gene:2504772499; PFAM: Pterin 4 alpha carbinolamine dehydratase.
  
  
 0.585
AEE49902.1
Sulphatase-modifying factor protein; COGs: COG1262 conserved hypothetical protein; InterPro IPR000601:IPR005532; KEGG: cts:Ctha_2336 hypothetical protein; PFAM: Sulphatase-modifying factor; PKD; SMART: PKD; SPTR: Putative uncharacterized protein; IMG reference gene:2504771383; PFAM: Formylglycine-generating sulfatase enzyme; PKD domain.
       0.507
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
  
  
 0.442
AEE51969.1
Phenylacetic acid degradation protein paaN; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR002539:IPR011966; KEGG: rmr:Rmar_1556 phenylacetic acid degradation protein PaaN; PFAM: MaoC-like dehydratase; Aldehyde dehydrogenase; PRIAM: Aldehyde dehydrogenase (NAD(+)); SPTR: NAD-dependent aldehyde dehydrogenases; TIGRFAM: Phenylacetic acid degradation protein paaN; IMG reference gene:2504773509; PFAM: MaoC like domain; Aldehyde dehydrogenase family; TIGRFAM: phenylacetic acid degradation protein paaN.
   
  
 0.401
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.