Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE50019.1Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: sli:Slin_5037 amidohydrolase; PFAM: Amidohydrolase 1; SPTR: Amidohydrolase; IMG reference gene:2504771501; PFAM: Amidohydrolase family. (426 aa)    
Predicted Functional Partners:
AEE50018.1
Metal-dependent phosphohydrolase HD sub domain protein; InterPro IPR003607:IPR006674; KEGG: paa:Paes_0935 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2504771500; PFAM: HD domain.
       0.757
AEE50020.1
Hypothetical protein; IMG reference gene:2504771502.
       0.757
AEE50844.1
COGs: COG2986 Histidine ammonia-lyase; InterPro IPR001106:IPR005921; KEGG: fjo:Fjoh_2576 histidine ammonia-lyase; PFAM: Phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Histidine ammonia-lyase; TIGRFAM: Histidine ammonia-lyase; IMG reference gene:2504772354; PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase.
  
  
 0.640
AEE53354.1
Amidohydrolase; COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR010168; KEGG: fbc:FB2170_13923 hypothetical protein; SPTR: Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase; IMG reference gene:2504774927; PFAM: Peptidase dimerisation domain; TIGRFAM: amidohydrolase.
 
     0.503
AEE50017.1
COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR011110:IPR011123; KEGG: sli:Slin_5621 PAS/PAC sensor signal transduction histidine kinase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Two component regulator three Y; Two component regulator propeller; PRIAM: Adenylate cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate cyclase; IMG reference gene:2504771499; PFAM: Adenylate and Guanylate cyclase catalytic domain; Y_Y_Y domain; Two component regulator propeller.
       0.489
AEE49621.1
KEGG: chu:CHU_1768 hypothetical protein; SPTR: Putative orphan protein; IMG reference gene:2504771093.
  
  
 0.488
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
  
  
 0.488
AEE51108.1
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: sli:Slin_6549 peptidase M28; PFAM: Peptidase M28; SPTR: Peptidase M28; IMG reference gene:2504772628; PFAM: PA domain; Peptidase family M28.
  
     0.475
AEE53891.1
COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: sli:Slin_1815 beta-lactamase; PFAM: Beta-lactamase-related; SPTR: Beta-lactamase; IMG reference gene:2504775471; PFAM: Beta-lactamase.
  
     0.471
AEE49158.1
Amidohydrolase 3; COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: sus:Acid_7369 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: Amidohydrolase 3; IMG reference gene:2504770624; PFAM: Amidohydrolase family.
  
     0.447
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (20%) [HD]