Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE50028.1Heme-binding protein; COGs: COG1413 FOG: HEAT repeat; InterPro IPR013427:IPR004155; KEGG: dfe:Dfer_4620 heme-binding protein; PFAM: PBS lyase HEAT-like repeat; SMART: PBS lyase HEAT-like repeat; SPTR: Heme-binding protein; TIGRFAM: Putative haem-binding region; IMG reference gene:2504771510; PFAM: PBS lyase HEAT-like repeat; TIGRFAM: putative membrane-bound dehydrogenase domain; putative heme-binding domain, Pirellula/Verrucomicrobium type. (1129 aa)    
Predicted Functional Partners:
AEE51429.1
COGs: COG4993 Glucose dehydrogenase; InterProIPR018391:IPR019551:IPR002372:IPR019556:IPR 003088; KEGG: dfe:Dfer_0311 pyrrolo-quinoline quinone; PFAM: PQQ-dependent enzyme, N-terminal; Pyrrolo-quinoline quinone repeat; PQQ-dependent enzyme, C-terminal; Cytochrome c, class I; PRIAM: Quinoprotein glucose dehydrogenase; SPTR: Pyrrolo-quinoline quinone; IMG reference gene:2504772956; PFAM: Pyrrolo-quinoline quinone coenzyme N-terminus; Cytochrome c; Pyrrolo-quinoline quinone coenzyme C-terminus; PQQ enzyme repeat.
  
 
 0.945
AEE50570.1
SMP-30/Gluconolaconase/LRE-like region-containing protein; COGs: COG3386 Gluconolactonase; InterPro IPR000801:IPR013658; KEGG: ote:Oter_3295 SMP-30/gluconolaconase/LRE domain-containing protein; PFAM: SMP-30/Gluconolaconase/LRE-like region; Putative esterase; SPTR: SMP-30/Gluconolaconase/LRE domain protein; IMG reference gene:2504772073; PFAM: SMP-30/Gluconolaconase/LRE-like region; Putative esterase.
 
  
  0.937
AEE48640.1
COGs: COG4993 Glucose dehydrogenase; InterPro IPR019551:IPR002372:IPR018391; KEGG: sus:Acid_6767 pyrrolo-quinoline quinone; PFAM: PQQ-dependent enzyme, N-terminal; Pyrrolo-quinoline quinone repeat; PRIAM: Quinoprotein glucose dehydrogenase; SPTR: Pyrrolo-quinoline quinone; IMG reference gene:2504770090; PFAM: Pyrrolo-quinoline quinone coenzyme N-terminus; PQQ enzyme repeat.
 
 
 0.922
AEE48634.1
COGs: COG3386 Gluconolactonase; InterPro IPR013658; KEGG: chu:CHU_3561 gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE-like region; PRIAM: Gluconolactonase; SPTR: Gluconolactonase; IMG reference gene:2504770084; PFAM: SMP-30/Gluconolaconase/LRE-like region.
 
  
  0.918
AEE49187.1
COGs: COG3386 Gluconolactonase; InterPro IPR013658; KEGG: dfe:Dfer_2426 gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE-like region; PRIAM: Gluconolactonase; SPTR: Gluconolactonase; IMG reference gene:2504770653; PFAM: SMP-30/Gluconolaconase/LRE-like region.
 
  
  0.915
AEE48633.1
SMP-30/Gluconolaconase/LRE-like region-containing protein; COGs: COG3386 Gluconolactonase; InterPro IPR013096:IPR013658; KEGG: rba:RB1022 gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE-like region; Cupin 2, conserved barrel; SPTR: SMP-30/Gluconolaconase/LRE domain protein; IMG reference gene:2504770083; PFAM: SMP-30/Gluconolaconase/LRE-like region; Cupin domain.
    
  0.904
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
  0.826
AEE54329.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...]
  
 
  0.818
AEE48570.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: sli:Slin_1998 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG reference gene:2504770018; PFAM: Glyceraldehyde 3-phosphate dehydrogenase [...]
    
 0.809
AEE51523.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: gpb:HDN1F_09550 2-ketoglutarate: nadp oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; PRIAM: 2-oxoglutarate synthase; SPTR: 2-ketoglutarate: nadp oxidoreductase, alpha subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504773052; PFAM: domain; Pyruvate ferredoxin/flav [...]
  
 
  0.807
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (20%) [HD]