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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AEE50084.1D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: cpi:Cpin_4725 D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase, N-terminal; FAD-linked oxidase, C-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: D-lactate dehydrogenase (Cytochrome); IMG reference gene:2504771569; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain. (973 aa)    
Predicted Functional Partners:
AEE53820.1
Lactate utilization protein B/C; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741:IPR001450; KEGG: cpi:Cpin_4921 protein of unknown function DUF162; PFAM: Protein of unknown function DUF162; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein; IMG reference gene:2504775398; PFAM: Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein.
  
 
 0.790
AEE53153.1
NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575; KEGG: pub:SAR11_0680 NAD-dependent formate dehydrogenase subunit beta; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NAD-dependent formate dehydrogenase beta subunit; IMG reference gene:2504774726; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase [...]
  
 0.685
AEE53821.1
Lactate utilization protein B/C; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: phe:Phep_2948 protein of unknown function DUF162; PFAM: Protein of unknown function DUF162; SPTR: Putative uncharacterized protein; IMG reference gene:2504775399; PFAM: Uncharacterised ACR, YkgG family COG1556.
  
 
 0.680
AEE48272.1
COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730; KEGG: cpi:Cpin_3760 electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein alpha/beta-subunit; IMG reference gene:2504769715; PFAM: Electron transfer flavoprotein domain.
  
 
 0.660
AEE48271.1
COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730:IPR014731; KEGG: cpi:Cpin_3759 electron transfer flavoprotein alpha subunit; PFAM: Electron transfer flavoprotein, alpha subunit, C-terminal; Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein alpha subunit; IMG reference gene:2504769714; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain.
  
 
 0.646
AEE50083.1
ThiJ/PfpI domain-containing protein; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR002818; KEGG: ava:Ava_4332 ThiJ/PfpI; PFAM: ThiJ/PfpI; SPTR: ThiJ/PfpI; IMG reference gene:2504771568; PFAM: DJ-1/PfpI family.
  
    0.583
AEE48523.1
COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262; KEGG: rxy:Rxyl_1052 lactate 2-monooxygenase; PFAM: FMN-dependent dehydrogenase; PRIAM: Lactate 2-monooxygenase; SPTR: Lactate 2-monooxygenase; IMG reference gene:2504769970; PFAM: FMN-dependent dehydrogenase.
  
 0.503
AEE52032.1
Isopentenyl-diphosphate Delta-isomerase; COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; KEGG: amr:AM1_4374 isopentenyl pyrophosphate isomerase; PRIAM: Isopentenyl-diphosphate Delta-isomerase; SPTR: Putative isopentenyl-diphosphate delta-isomerase; IMG reference gene:2504773572; PFAM: FMN-dependent dehydrogenase; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 2.
  
 0.503
AEE48355.1
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: lby:Lbys_0673 allosteric nADP-dependent malic enzyme; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SPTR: Allosteric NADP-dependent malic enzyme; IMG reference gene:2504769800; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
  
  
 0.489
AEE54329.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: mca:MCA0769 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate ferredoxin/fla [...]
     
 0.486
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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