Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE50171.1Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. (530 aa)    
Predicted Functional Partners:
AEE48503.1
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: lby:Lbys_3060 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504769950; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
     
  0.900
AEE51846.1
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: dfe:Dfer_5278 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; IMG reference gene:2504773383; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
     
  0.900
AEE53609.1
Carboxylate-amine ligase ybdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
AEE53822.1
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: phe:Phep_3731 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltranspeptidase periplasmic; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504775400; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
     
  0.900
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.824
AEE52161.1
COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sli:Slin_5637 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionine beta-lyase; IMG reference gene:2504773703; PFAM: Cys/Met metabolism PLP-dependent enzyme.
   
 
  0.803
AEE48112.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II.
     
  0.800
AEE53974.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: phe:Phep_1507 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504775554; PFAM: Aminotransferase class I and II.
     
  0.800
AEE50172.1
SPTR: Putative uncharacterized protein; IMG reference gene:2504771661.
       0.773
AEE53969.1
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR007865:IPR000994; KEGG: gfo:GFO_0851 secreted Xaa-Pro aminopeptidase; PFAM: Peptidase M24, structural domain; Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal; SPTR: Metallopeptidase family M24; IMG reference gene:2504775549; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24.
 
 
 0.616
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (16%) [HD]