| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE48112.1 | AEE50171.1 | Halhy_0199 | Halhy_2292 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | 0.800 |
| AEE48112.1 | AEE52161.1 | Halhy_0199 | Halhy_4317 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sli:Slin_5637 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionine beta-lyase; IMG reference gene:2504773703; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.914 |
| AEE48112.1 | AEE53609.1 | Halhy_0199 | Halhy_5786 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | Carboxylate-amine ligase ybdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.800 |
| AEE48112.1 | AEE53974.1 | Halhy_0199 | Halhy_6152 | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: phe:Phep_1507 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504775554; PFAM: Aminotransferase class I and II. | 0.918 |
| AEE48503.1 | AEE50171.1 | Halhy_0594 | Halhy_2292 | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: lby:Lbys_3060 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504769950; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | 0.900 |
| AEE48503.1 | AEE51846.1 | Halhy_0594 | Halhy_3998 | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: lby:Lbys_3060 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504769950; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: dfe:Dfer_5278 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; IMG reference gene:2504773383; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | 0.927 |
| AEE48503.1 | AEE53609.1 | Halhy_0594 | Halhy_5786 | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: lby:Lbys_3060 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504769950; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | Carboxylate-amine ligase ybdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.913 |
| AEE48503.1 | AEE53822.1 | Halhy_0594 | Halhy_5999 | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: lby:Lbys_3060 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504769950; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: phe:Phep_3731 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltranspeptidase periplasmic; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504775400; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | 0.903 |
| AEE50171.1 | AEE48112.1 | Halhy_2292 | Halhy_0199 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: lby:Lbys_2637 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aminotransferase class I and II; IMG reference gene:2504769551; PFAM: Aminotransferase class I and II. | 0.800 |
| AEE50171.1 | AEE48503.1 | Halhy_2292 | Halhy_0594 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: lby:Lbys_3060 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504769950; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | 0.900 |
| AEE50171.1 | AEE50172.1 | Halhy_2292 | Halhy_2293 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | SPTR: Putative uncharacterized protein; IMG reference gene:2504771661. | 0.773 |
| AEE50171.1 | AEE51846.1 | Halhy_2292 | Halhy_3998 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: dfe:Dfer_5278 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; IMG reference gene:2504773383; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | 0.900 |
| AEE50171.1 | AEE52161.1 | Halhy_2292 | Halhy_4317 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sli:Slin_5637 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionine beta-lyase; IMG reference gene:2504773703; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.803 |
| AEE50171.1 | AEE53609.1 | Halhy_2292 | Halhy_5786 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | Carboxylate-amine ligase ybdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.900 |
| AEE50171.1 | AEE53822.1 | Halhy_2292 | Halhy_5999 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: phe:Phep_3731 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltranspeptidase periplasmic; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504775400; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | 0.900 |
| AEE50171.1 | AEE53969.1 | Halhy_2292 | Halhy_6147 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR007865:IPR000994; KEGG: gfo:GFO_0851 secreted Xaa-Pro aminopeptidase; PFAM: Peptidase M24, structural domain; Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal; SPTR: Metallopeptidase family M24; IMG reference gene:2504775549; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24. | 0.616 |
| AEE50171.1 | AEE53974.1 | Halhy_2292 | Halhy_6152 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: phe:Phep_1507 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504775554; PFAM: Aminotransferase class I and II. | 0.800 |
| AEE50171.1 | glyA | Halhy_2292 | Halhy_2715 | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.824 |
| AEE50172.1 | AEE50171.1 | Halhy_2293 | Halhy_2292 | SPTR: Putative uncharacterized protein; IMG reference gene:2504771661. | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: zpr:ZPR_1992 putative metallopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; SPTR: Aminopeptidase, putative; IMG reference gene:2504771660; PFAM: Peptidase family M1. | 0.773 |
| AEE51846.1 | AEE48503.1 | Halhy_3998 | Halhy_0594 | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: dfe:Dfer_5278 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; IMG reference gene:2504773383; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: lby:Lbys_3060 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504769950; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase. | 0.927 |