Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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AEE50174.1Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR005746:IPR013766; KEGG: phe:Phep_1679 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; IMG reference gene:2504771663; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. (101 aa)    
Predicted Functional Partners:
AEE53705.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR005982:IPR013027; KEGG: phe:Phep_1613 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin-disulfide reductase; TIGRFAM: Thioredoxin reductase; IMG reference gene:2504775280; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
 
 
 0.629
AEE50211.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.615
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.593
groL-2
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.593
AEE50173.1
KEGG: saf:SULAZ_1687 phosphate-selective porin O and P superfamily protein; SPTR: Phosphate-selective porin O and P superfamily protein; IMG reference gene:2504771662.
  
    0.582
AEE50175.1
COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: mtt:Ftrac_3213 nitroreductase; PFAM: Nitroreductase-like; SPTR: Iodotyrosine dehalogenase protein; IMG reference gene:2504771664; PFAM: Nitroreductase family.
   
 
 0.571
AEE50452.1
Response regulator receiver protein; COGs: COG0492 Thioredoxin reductase; InterPro IPR001789:IPR013027; KEGG: sli:Slin_6098 response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Signal transduction response regulator, receiver region; PRIAM: Thioredoxin-disulfide reductase; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; IMG reference gene:2504771953; PFAM: [...]
  
 
 0.538
AEE49080.1
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: chu:CHU_3776 glutamate synthase (NADH) large subunit; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (NADH) large subunit; IMG reference gene:2504770544; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
   
 
 0.535
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
  
 
 
 0.527
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 
 0.523
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
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