| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE50280.1 | AEE50281.1 | Halhy_2405 | Halhy_2406 | KEGG: cpi:Cpin_1118 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771774. | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | 0.836 |
| AEE50280.1 | AEE50282.1 | Halhy_2405 | Halhy_2407 | KEGG: cpi:Cpin_1118 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771774. | COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: rmr:Rmar_2175 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: Putative uncharacterized protein; IMG reference gene:2504771776; PFAM: Protein of unknown function (DUF1015). | 0.561 |
| AEE50280.1 | AEE52957.1 | Halhy_2405 | Halhy_5131 | KEGG: cpi:Cpin_1118 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771774. | Protein of unknown function DUF458, RNase H; COGs: COG1978 conserved hypothetical protein; InterPro IPR007405; KEGG: cpi:Cpin_7091 protein of unknown function DUF458; PFAM: Protein of unknown function DUF458, RNase H-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504774529; PFAM: Protein of unknown function (DUF458). | 0.755 |
| AEE50280.1 | mqnB | Halhy_2405 | Halhy_0301 | KEGG: cpi:Cpin_1118 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771774. | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.476 |
| AEE50281.1 | AEE50280.1 | Halhy_2406 | Halhy_2405 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | KEGG: cpi:Cpin_1118 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771774. | 0.836 |
| AEE50281.1 | AEE50282.1 | Halhy_2406 | Halhy_2407 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: rmr:Rmar_2175 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: Putative uncharacterized protein; IMG reference gene:2504771776; PFAM: Protein of unknown function (DUF1015). | 0.779 |
| AEE50281.1 | AEE51185.1 | Halhy_2406 | Halhy_3326 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | FO synthase, subunit 2; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR006638:IPR020050:IPR007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; TIGRFAM: FO synthase, subunit 2; IMG reference gene:2504772706; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | 0.744 |
| AEE50281.1 | AEE52957.1 | Halhy_2406 | Halhy_5131 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | Protein of unknown function DUF458, RNase H; COGs: COG1978 conserved hypothetical protein; InterPro IPR007405; KEGG: cpi:Cpin_7091 protein of unknown function DUF458; PFAM: Protein of unknown function DUF458, RNase H-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504774529; PFAM: Protein of unknown function (DUF458). | 0.659 |
| AEE50281.1 | AEE53223.1 | Halhy_2406 | Halhy_5398 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371:IPR000537; KEGG: cpi:Cpin_1902 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; IMG reference gene:2504774796; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.709 |
| AEE50281.1 | mqnA | Halhy_2406 | Halhy_5956 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.759 |
| AEE50281.1 | mqnB | Halhy_2406 | Halhy_0301 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.976 |
| AEE50281.1 | mqnD | Halhy_2406 | Halhy_5876 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.658 |
| AEE50281.1 | mqnE | Halhy_2406 | Halhy_5958 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | FO synthase, subunit 2; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.974 |
| AEE50281.1 | ubiX | Halhy_2406 | Halhy_5366 | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.648 |
| AEE50282.1 | AEE50280.1 | Halhy_2407 | Halhy_2405 | COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: rmr:Rmar_2175 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: Putative uncharacterized protein; IMG reference gene:2504771776; PFAM: Protein of unknown function (DUF1015). | KEGG: cpi:Cpin_1118 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504771774. | 0.561 |
| AEE50282.1 | AEE50281.1 | Halhy_2407 | Halhy_2406 | COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: rmr:Rmar_2175 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: Putative uncharacterized protein; IMG reference gene:2504771776; PFAM: Protein of unknown function (DUF1015). | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | 0.779 |
| AEE51185.1 | AEE50281.1 | Halhy_3326 | Halhy_2406 | FO synthase, subunit 2; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR006638:IPR020050:IPR007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; TIGRFAM: FO synthase, subunit 2; IMG reference gene:2504772706; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: phe:Phep_3845 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase 1; IMG reference gene:2504771775; PFAM: Amidohydrolase family. | 0.744 |
| AEE51185.1 | AEE53223.1 | Halhy_3326 | Halhy_5398 | FO synthase, subunit 2; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR006638:IPR020050:IPR007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; TIGRFAM: FO synthase, subunit 2; IMG reference gene:2504772706; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371:IPR000537; KEGG: cpi:Cpin_1902 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase related; IMG reference gene:2504774796; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.792 |
| AEE51185.1 | mqnA | Halhy_3326 | Halhy_5956 | FO synthase, subunit 2; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR006638:IPR020050:IPR007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; TIGRFAM: FO synthase, subunit 2; IMG reference gene:2504772706; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.944 |
| AEE51185.1 | mqnB | Halhy_3326 | Halhy_0301 | FO synthase, subunit 2; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR006638:IPR020050:IPR007197; KEGG: phe:Phep_1588 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; TIGRFAM: FO synthase, subunit 2; IMG reference gene:2504772706; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family. | Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.979 |
