Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE50442.1InterPro IPR003594; KEGG: mpi:Mpet_2164 ATP-binding region ATPase domain-containing protein; PFAM: ATP-binding region, ATPase-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504771942; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (493 aa)    
Predicted Functional Partners:
AEE50441.1
InterPro IPR018310; KEGG: mpi:Mpet_2165 putative endonuclease, Z1 domain-containing protein; PFAM: Putative endonuclease, Z1 domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504771941; PFAM: Z1 domain.
 
 
 0.946
AEE50443.1
DNA-cytosine methyltransferase; COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525; KEGG: cpi:Cpin_2562 DNA-cytosine methyltransferase; PFAM: DNA methylase, C-5 cytosine-specific; SPTR: DNA-cytosine methyltransferase; TIGRFAM: DNA methylase, C-5 cytosine-specific; IMG reference gene:2504771943; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm).
 
     0.917
AEE48774.1
COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623:IPR002939; KEGG: fjo:Fjoh_2374 chaperone DnaJ domain-containing protein; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone DnaJ domain protein; IMG reference gene:2504770230; PFAM: DnaJ domain; DnaJ C terminal region.
  
 0.850
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.850
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.820
AEE52920.1
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR013126; KEGG: sli:Slin_5724 TIR protein; PFAM: Heat shock protein 70; SPTR: TIR protein; IMG reference gene:2504774492; PFAM: Hsp70 protein.
   
 0.820
AEE52926.1
Heat shock protein; COGs: COG0443 Molecular chaperone; KEGG: chu:CHU_2145 heat shock protein; SPTR: Probable heat shock protein; IMG reference gene:2504774498; PFAM: Hsp70 protein.
   
 0.820
groL-2
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.820
AEE53655.1
Heat shock protein 70; COGs: COG0443 Molecular chaperone; InterPro IPR013126; KEGG: phe:Phep_3231 Fe-S protein assembly chaperone HscA; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70; IMG reference gene:2504775230; PFAM: Hsp70 protein; TIGRFAM: Fe-S protein assembly chaperone HscA.
   
 0.820
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.820
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.