| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE49495.1 | AEE51077.1 | Halhy_1604 | Halhy_3217 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: cpi:Cpin_6908 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504772597; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.900 |
| AEE49495.1 | AEE51353.1 | Halhy_1604 | Halhy_3498 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | 5 nucleotidase deoxy cytosolic type C; COGs: COG4502 conserved hypothetical protein; InterPro IPR010708; KEGG: sli:Slin_1355 5 nucleotidase deoxy cytosolic type C; SPTR: 5 nucleotidase deoxy cytosolic type C; IMG reference gene:2504772879; PFAM: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). | 0.902 |
| AEE49495.1 | AEE53216.1 | Halhy_1604 | Halhy_5391 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR000362:IPR013539; KEGG: coc:Coch_1238 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal; Fumarate lyase; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504774789; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.906 |
| AEE49495.1 | AEE53950.1 | Halhy_1604 | Halhy_6128 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: sli:Slin_4342 metallophosphoesterase; PFAM: Metallophosphoesterase; PRIAM: 5'-nucleotidase; SPTR: Metallophosphoesterase; IMG reference gene:2504775530; PFAM: Calcineurin-like phosphoesterase. | 0.946 |
| AEE49495.1 | gmk | Halhy_1604 | Halhy_2597 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.902 |
| AEE49495.1 | guaA | Halhy_1604 | Halhy_0188 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.905 |
| AEE49495.1 | surE | Halhy_1604 | Halhy_5066 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.907 |
| AEE50211.1 | gmk | Halhy_2334 | Halhy_2597 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.907 |
| AEE50211.1 | guaA | Halhy_2334 | Halhy_0188 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.450 |
| AEE50211.1 | ndk | Halhy_2334 | Halhy_0350 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.915 |
| AEE50465.1 | gmk | Halhy_2596 | Halhy_2597 | Conserved hypothetical protein CHP00255; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR005229:IPR013527:IPR013551; KEGG: phe:Phep_4196 hypothetical protein; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732; SPTR: YicC domain protein; TIGRFAM: Conserved hypothetical protein CHP00255; IMG reference gene:2504771967; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.929 |
| AEE51077.1 | AEE49495.1 | Halhy_3217 | Halhy_1604 | COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: cpi:Cpin_6908 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504772597; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | 0.900 |
| AEE51077.1 | AEE51353.1 | Halhy_3217 | Halhy_3498 | COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: cpi:Cpin_6908 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504772597; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 5 nucleotidase deoxy cytosolic type C; COGs: COG4502 conserved hypothetical protein; InterPro IPR010708; KEGG: sli:Slin_1355 5 nucleotidase deoxy cytosolic type C; SPTR: 5 nucleotidase deoxy cytosolic type C; IMG reference gene:2504772879; PFAM: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). | 0.900 |
| AEE51077.1 | AEE53950.1 | Halhy_3217 | Halhy_6128 | COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: cpi:Cpin_6908 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504772597; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: sli:Slin_4342 metallophosphoesterase; PFAM: Metallophosphoesterase; PRIAM: 5'-nucleotidase; SPTR: Metallophosphoesterase; IMG reference gene:2504775530; PFAM: Calcineurin-like phosphoesterase. | 0.913 |
| AEE51077.1 | gmk | Halhy_3217 | Halhy_2597 | COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: cpi:Cpin_6908 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504772597; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.939 |
| AEE51077.1 | guaA | Halhy_3217 | Halhy_0188 | COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: cpi:Cpin_6908 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504772597; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.948 |
| AEE51077.1 | surE | Halhy_3217 | Halhy_5066 | COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: cpi:Cpin_6908 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504772597; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.915 |
| AEE51353.1 | AEE49495.1 | Halhy_3498 | Halhy_1604 | 5 nucleotidase deoxy cytosolic type C; COGs: COG4502 conserved hypothetical protein; InterPro IPR010708; KEGG: sli:Slin_1355 5 nucleotidase deoxy cytosolic type C; SPTR: 5 nucleotidase deoxy cytosolic type C; IMG reference gene:2504772879; PFAM: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: ava:Ava_3996 metallophosphoesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: Metallophosphoesterase; IMG reference gene:2504770965; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. | 0.902 |
| AEE51353.1 | AEE51077.1 | Halhy_3498 | Halhy_3217 | 5 nucleotidase deoxy cytosolic type C; COGs: COG4502 conserved hypothetical protein; InterPro IPR010708; KEGG: sli:Slin_1355 5 nucleotidase deoxy cytosolic type C; SPTR: 5 nucleotidase deoxy cytosolic type C; IMG reference gene:2504772879; PFAM: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). | COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: cpi:Cpin_6908 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504772597; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.900 |
| AEE51353.1 | AEE53216.1 | Halhy_3498 | Halhy_5391 | 5 nucleotidase deoxy cytosolic type C; COGs: COG4502 conserved hypothetical protein; InterPro IPR010708; KEGG: sli:Slin_1355 5 nucleotidase deoxy cytosolic type C; SPTR: 5 nucleotidase deoxy cytosolic type C; IMG reference gene:2504772879; PFAM: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). | COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR000362:IPR013539; KEGG: coc:Coch_1238 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal; Fumarate lyase; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504774789; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.900 |
