Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE50539.1Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: cpi:Cpin_5626 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family protein; IMG reference gene:2504772042; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain. (283 aa)    
Predicted Functional Partners:
AEE49242.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: zpr:ZPR_3198 sugar-binding sensor histidine kinase/response regulator hybrid; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504770708; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.609
AEE51022.1
Transcriptional regulator, AraC family; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR018060:IPR000005; KEGG: rbi:RB2501_11087 AraC family transcriptional regulator; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Phenazine biosynthesis PhzC/PhzF protein; IMG reference gene:2504772541.
  
     0.567
AEE48615.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: cpi:Cpin_6199 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator; IMG reference gene:2504770065; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.543
AEE50538.1
KEGG: cpi:Cpin_2508 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504772041.
       0.531
AEE49110.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR003313:IPR000005:IPR018060; KEGG: dfe:Dfer_4283 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; AraC protein, arabinose-binding/dimerisation; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504770574; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.527
AEE50537.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: cpi:Cpin_5629 short chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2504772040; PFAM: short chain dehydrogenase.
 
     0.513
AEE51679.1
Transcriptional regulator, AraC family; COGs: COG4275 conserved hypothetical protein; InterPro IPR018060:IPR018634:IPR000005; KEGG: dfe:Dfer_2046 transcriptional regulator, AraC family; PFAM: Chromate resistance exported protein; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504773211; PFAM: Chromate resistance exported protein; Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.500
AEE50535.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR013027; KEGG: chu:CHU_2572 alkyl hydroperoxide reductase, F52a subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Alkyl hydroperoxide reductase, F52a subunit; IMG reference gene:2504772038; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
 
     0.492
AEE53667.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005; KEGG: cyc:PCC7424_1148 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2504775242; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.483
AEE52327.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: rmr:Rmar_2599 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: RegA, putative; IMG reference gene:2504773874; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
  
     0.477
Your Current Organism:
Haliscomenobacter hydrossis
NCBI taxonomy Id: 760192
Other names: H. hydrossis DSM 1100, Haliscomenobacter hydrossis DSM 1100
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.